Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID14879	Olaparib	GSE70138	HUVEC	Human	24h	0.12uM	EID0083

Response Information :

Types	Number	Response transcription factors
Up-regulation	133	SSX3; CCNC; NFIL3; IRF2; PHIP; CNOT1; KLF1; NANOG; HDAC2; ZNF140; ZNF217; RAD21; ACTL6A; ADNP; SUB1; HOXA1; MYT1; STAT5A; MED4; CITED1; ZSCAN18; FOXA2; SMARCA2; SNAI2; GATA2; KAT2B; RNF111; TMF1; MYB; NPAT; CNOT6; RBL1; SP2; TLE2; CREB3L2; TEAD1; CBFA2T3; NR4A1; KLF2; FOXI1; MYF6; TOB1; NR4A3; CTNNB1; REST; NR4A2; LITAF; RNF6; HLTF; RBPMS; BHLHE40; ZNF124; CBX7; ZNF148; EN2; NCOA2; PROX1; NFIB; SOX10; SMAD7; JARID2; BRCA1; CREBL2; SSX1; C1D; NFE2; ZBTB18; BHLHE41; HES1; ZNF532; UBE3A; PHF20; DLX5; JAK2; TDP2; ZBTB20; ID4; ZNF529; E2F5; WT1; NR3C1; ZNF516; MITF; YEATS4; MED21; BAZ2B; TOPORS; ZNF329; MNAT1; ZBED2; ZNF331; CDK8; MEOX1; TFDP2; ING3; VGLL4; MYCN; ZHX2; TBL1XR1; NR1D2; BACH1; NFATC1; RSF1; FOSB; SOX11; TRIM24; NEUROD1; KAT6B; PEG3; CBX3; ZNF443; HDAC9; AFF1; ATF1; GATA6; NFE2L3; ZFPM2; ZEB1; EGR3; AEBP1; TBX3; HMGB1; TCF4; BMI1; ZFP36L2; BCL11A; HMGN3; OSR2; TRIM29; PSIP1; TOX3; TXNIP; EGR2
Down-regulation	95	PUF60; CRK; SOX4; FOSL1; ETS1; NFKBIA; PSMD9; KAT5; SSRP1; SMARCD2; CARM1; TRIM28; FOXM1; NELFB; PA2G4; ATF6; ATF4; SMARCB1; CEBPG; UBE2I; CNOT3; FLNA; CHD8; HDAC3; ZNF384; ZFP36L1; SREBF1; MKL1; KAT8; AATF; TFDP1; HSF1; RFXANK; ENO1; CBX6; BCL6; DEAF1; TGFB1; ABL1; SND1; KLF6; HOXB6; PSMC3; HDGF; SUPT6H; NFE2L1; NEDD8; FOXK2; RUVBL2; EDF1; CIZ1; THAP4; HMGA1; RORA; TAF1D; MED15; CARHSP1; SAP18; TRIP6; BCL3; UBE2L3; WHSC1; BRD4; LOXL2; IRF8; RBM39; MAX; MTA1; MED1; BTG1; HOXB7; ZNF91; MBD2; SCAND1; TOX; APEX1; MECOM; HLX; EMX2; ATF5; KLF7; HOXB2; NR2F2; FOXA1; TP53; ID1; THAP11; NR2F6; HTATIP2; IRF6; HIRA; BASP1; NFATC3; CITED2; KDM5D