Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID14805	Rucaparib	GSE70138	HUVEC	Human	24h	10uM	EID0082

Response Information :

Types	Number	Response transcription factors
Up-regulation	94	MEF2C; IKBKAP; ID2; TAF9B; HIVEP2; NFRKB; PLAGL1; NR0B1; STAT4; ZNF131; TRIM32; KDM5A; PGR; BTAF1; SOX17; SATB2; HOXC6; HOXC5; FOXJ3; NLK; HDAC5; ZNF217; ORC2; EGR3; UBE2B; WDR77; MECP2; ID4; SUPT3H; CHD1; DLX5; IRX5; OSR2; CERS6; LMCD1; HIPK1; BAZ2A; PHF20; STAT5A; IRF7; PHF1; ZNF248; CTNNB1; EN2; NFATC1; SSBP2; NFE2; TXNIP; FOXN3; MLXIP; ARID5B; PPP1R13L; NR4A1; TRPS1; KMT2A; NEUROD1; TGFB1I1; HIVEP1; TWIST1; ZBED2; WWP1; ELF5; HIPK3; NFIB; WT1; PCGF2; NR1D2; HHEX; ELK3; ZNF589; KDM5D; HLF; HDAC9; ETS2; YAP1; ST18; ZNF432; PBXIP1; NKX3-1; KLF2; GATA6; JUNB; TFAP2C; TCF21; EGR1; PEG3; VDR; ZFPM2; ATF3; CITED2; AEBP1; ZSCAN18; WWTR1; MEIS1
Down-regulation	84	CRK; IFI16; MAFF; TAF9; ZNF669; CBX3; APEX1; DNAJC2; TLE1; CBFB; BNC2; MBD2; MAF; NR2F2; HOXB5; TRIP4; KLF9; CTBP1; TRIP6; CENPB; CENPF; TCF7; ZNF281; ASCL1; ZKSCAN1; RAN; TULP4; HIPK2; PURA; MAFB; MNT; CUX1; DDX17; NPM1; DACH1; CDIP1; MNDA; RBBP8; ZNF302; MKL2; ZFHX4; COPS2; ITGB3BP; ZNF394; SMARCC2; HEY1; NAB1; CITED1; MYRF; HMGB2; NRIP1; NR2F1; SMAD2; VGLL4; TAL1; SOX9; CREBL2; CTR9; RREB1; LOXL2; PAX5; RNF141; FOXO1; ZNF160; SAP30; PTRF; LITAF; HOXB7; HMGB1; EYA1; SALL1; HOXB6; MEOX2; IRF8; BASP1; FOXF1; ZIC1; ZFP36L1; HOXB2; INSM1; PSIP1; ZNF91; SOX11; NFATC3