Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID14652 Nvp-bgj398 GSE70138 HUVEC Human 24h 0.12uM EID0045
Types Number Response transcription factors
Up-regulation 123 HDAC6; CEBPD; ESRRG; GATA3; SMAD1; ZNF768; MECOM; MED13; ZNF672; ESR1; CNOT6; BRCA1; MYT1; WWP1; NFE2L2; TRIM33; FHL5; THAP4; CHD3; MBD4; ZNF589; ZNF415; MEOX1; VAX2; PBX2; BRWD1; NEUROD1; ZNF227; DLX4; UIMC1; ZNF253; E2F5; L3MBTL1; RELA; ZSCAN16; RSF1; AFF1; EYA2; CDK2; KAT2B; ETS2; ZFHX3; ZNF226; KDM5A; RNF4; HIVEP1; PRMT2; TEAD3; ENY2; PGR; SALL1; DMTF1; MYBL1; AES; FOXA2; ZNF623; IRF2; NFYB; NCOR2; TLE2; HOXB5; ZSCAN31; DACH1; NKX2-1; CREB3; THAP1; ZBED1; SOX17; GATA2; BAZ2B; MAGED1; TTF2; BCOR; BHLHE41; ERBB4; IRF9; HMGN3; CAMTA1; BRD4; TERF2; TCF4; NHLH2; SUZ12; ZNF12; E2F8; PDLIM1; PFDN5; EMX2; BTG1; JAK2; MYCN; CERS6; SSBP2; STAT1; ZNF189; HEY2; SOX13; INSM1; IFI16; BRD2; CRY1; BCL11A; DAXX; DLX5; HMGB3; LEF1; KAT6A; ZNF165; HOXB2; NPAS2; TSC22D1; FOXF2; HDAC9; ASCL1; NRIP1; TXNIP; ZBTB16; ARNT2; EGR2; ATF3; RUNX3; WT1; MEIS1
Down-regulation 96 C1QBP; HMGA2; APEX1; WWTR1; PARP1; ABL1; MNT; PSMD9; HOXA1; SOX10; BNC2; TOB1; TGIF1; HIPK2; HAND1; TCF7L2; DPF2; KLF13; HMGXB4; NCOA6; ELF5; MDM2; TAF10; SUPT4H1; ZNF146; SNAI2; VPS72; TGFB1I1; EN1; PMF1; DBP; RBL2; EED; NR1H3; RNF138; TULP4; GFI1B; ZNF593; HHEX; TRIM28; HLTF; FOXN3; CITED2; CBFB; ARL2BP; MED24; NR1D2; ZNF573; POLR2A; ZNF91; TRIP6; NAB1; ZNF512B; HIC2; VGLL4; HDAC1; RBPMS; SSRP1; JUP; SMARCD3; LIN28A; PUF60; PMS1; BRD7; HOXC6; ID3; ZFHX4; SATB2; MLXIP; MYRF; ZNF652; ERBB2; ZNF281; TLE4; BATF; KLF11; MITF; ISL1; DEAF1; KLF9; ZFP36L2; MED1; ZBTB18; ZNF131; DNMT3B; CALR; HMGB2; TGFB1; MAFB; ID1; FOXG1; SUV39H1; TBX2; TCFL5; NR3C1; RELB