Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID14638	Idelalisib	GSE70138	HUVEC	Human	24h	1.11uM	EID0045

Response Information :

Types	Number	Response transcription factors
Up-regulation	137	ZNF22; HMGB3; ADRB2; NCOA3; PGR; GCM1; FHL5; ZNF516; PATZ1; NKRF; BCL6; SIAH2; E2F2; ZNF510; PITX2; ASCL1; HMG20A; ZBTB44; CHD8; RCOR1; ENO1; MITF; ETS2; MDM4; MXI1; MNT; NEUROD1; SOHLH2; ZNF507; SNAI1; TCEB2; CHD9; JUP; TRIM32; LHX3; HLX; ZNF141; NKX2-1; WNT4; MYF6; ZBTB43; SOX12; ZNF34; SMAD7; ZNF184; RARA; PHOX2B; NLK; TTF2; KLF10; SSX1; NCOR2; ZNF248; DACH1; SPEN; MAGED1; BAZ1A; TCF12; BRCA2; NCOA6; RORA; BRD2; HR; GATAD2A; THRA; PHF20; DAXX; ARID1A; MYB; RFX7; SIM1; FOXO3; IRF9; ZBED4; CNOT1; HDGF; ZNF410; UBE2I; ZEB2; TP63; NRBF2; KDM5D; NR4A2; YAP1; NRIP1; SMAD2; TAL1; ZNF551; ELF1; BACH2; ZSCAN31; PLAGL1; TLE4; KLF11; PRPF6; HOXA5; HDAC5; NAB1; FOSL2; SP3; TSC22D2; ZBTB16; ZNF529; MYBL1; BTG1; ZNF711; TCF21; TOX3; RAD21; IRF4; PAWR; KLF4; CUX2; GATA2; ZNF43; KAT6A; TBX2; HMGN3; ZNF107; MYCL; KLF5; MED1; ESR1; SOX11; TBX3; SPIB; INSM1; ZBTB18; EGR2; ZBTB20; LEF1; KLF6; TCF4; OSR2; WT1; EGR3; MEIS1
Down-regulation	85	LOXL2; TRIP6; THAP11; POLR3F; HLTF; TEAD1; USP16; TCEA1; DEAF1; ZBED2; ZNF266; NANOG; WWP1; PIAS2; ZHX2; BHLHE41; DLX2; IRF1; NKX2-2; FOXF2; CBX6; PBX1; PRRX1; TDP2; CTBP1; ZNF160; MLX; HOXB13; FUBP1; ZNF264; PTRF; HHEX; TAF9B; SOX9; CREBL2; CEBPG; ARNTL; TRRAP; TGFB1; NPAS2; COPS5; ZBTB38; SIX1; ZEB1; ZNF652; DNMT3B; DDIT3; CTR9; TADA3; EYA2; CBFB; ZNF721; SIM2; ZNF91; KAT2B; HDAC9; BBX; CITED1; SOX13; EHF; MEIS2; FOXC1; BMI1; NKX3-1; PITX1; FOXF1; CD3D; SMARCA1; MAF; TRIM22; ERBB2; HEY1; MSX1; HOXC10; MECOM; PAX5; TSC22D1; TRPS1; ID2; LITAF; MAFB; TCFL5; SSBP2; RELB; NR3C1