Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID14617	Osimertinib	GSE70138	HUVEC	Human	24h	0.04uM	EID0045

Response Information :

Types	Number	Response transcription factors
Up-regulation	87	FOS; EMX2; MAGED1; SERTAD2; BCLAF1; CDK9; ZNF136; NR1D2; DNAJC2; HSF2; TAF9B; E2F2; NFYA; PHOX2B; CHD1; KDM5A; GTF2I; ZBTB11; ING2; HIVEP2; JUNB; SMARCA2; ZSCAN31; NCOA1; TOB1; HMGN3; SUB1; BBX; CEBPZ; PHIP; HLTF; ASCL1; ZNF652; ZBTB20; NFIB; MEIS2; CTNNB1; WWTR1; NCOR2; FUBP1; PIR; ZNF148; MAFF; PMS1; ACTL6A; CBFB; TULP4; SSBP2; RBBP7; GRHL2; TAF10; ID4; CCNE1; TFAM; NELFB; SMARCA1; PTRF; OSR2; NRIP1; SMAD2; TOX3; IRX5; ERG; KLF9; PBX3; KLF10; HMGB2; NFAT5; INSM1; RBPMS; HEY1; HHEX; BHLHE41; CTBP2; TSC22D1; ZBTB38; GTF3A; AEBP1; ATF3; HLF; KLF2; TRPS1; AHR; PSIP1; KDM5D; PEG3; PUF60
Down-regulation	57	C1QBP; KLF5; MAFG; CDX1; NAB1; EGR2; YAP1; NFE2L3; PITX2; PLAGL2; CRK; NFYC; YWHAB; ZNF654; SKI; ZBTB7A; CARM1; ZNF85; IRF9; NR1H2; ETV5; NPAT; RBPJ; ZNF124; ZNF160; MAFB; ZNF430; BIRC2; CD3D; IRF7; PQBP1; CITED2; ZNF281; TAF5; NR2F6; TCEA2; HOXB5; ETV1; ZBTB16; CEBPB; MAZ; HOXB2; STAT1; SIX1; ZNF91; TGFB1; MNDA; MAF; HOXB6; SMAD7; POU2AF1; SATB2; GATA6; ZNF131; LITAF; TWIST1; RELB