Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID14615	Osimertinib	GSE70138	HUVEC	Human	24h	0.37uM	EID0045

Response Information :

Types	Number	Response transcription factors
Up-regulation	63	GATA3; NKX2-2; SALL1; C1QBP; MXI1; OLIG2; MAGED1; DEK; PHOX2B; PDLIM1; TMF1; IRF2; TCF4; MITF; ESR1; URI1; NR4A2; FOSL2; SP2; DDX5; YBX1; TCF12; MYCL; RBBP8; WWTR1; SUZ12; TAF7; TFEC; INSM1; ERBB2; DAXX; PNRC1; HMGB1; SOX17; ZNF516; MED1; CREBL2; RBBP7; MSX1; PITX1; IRF4; CREB3L1; ERBB4; ST18; HMGB2; TBX3; HEY1; WWC1; TOB1; PBX1; BHLHE41; HOXB2; TWIST1; HMGN3; ID4; GATA6; ZBTB18; PBX3; ZNF423; ARNT2; WT1; MEIS2; PEG3
Down-regulation	39	RNF14; RREB1; ARRB1; MAX; KLF7; ELF3; NR2F2; SREBF1; SAP18; CDYL; TCF21; FOXC1; NCOA1; RBFOX2; CDK8; STAT4; IL16; HOXC6; PEX2; PLAGL1; HOXB7; HOXD1; KLF4; PFDN5; NFATC1; FOSB; SMARCA2; NR2F1; JUP; STAT1; HOXC10; KLF9; RUNX3; HOXB6; DACH1; SOX9; SSBP2; RELB; E2F2