Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID14614	Osimertinib	GSE70138	HUVEC	Human	24h	1.11uM	EID0045

Response Information :

Types	Number	Response transcription factors
Up-regulation	59	HIVEP2; ZNF443; JUNB; RBM39; SIAH2; IKBKAP; ZFHX3; ZNF337; ZNF248; ZNF263; MTDH; TRIM32; EYA2; PBX2; SETD2; ST18; ELF3; RUNX1; MAFF; INSR; SMAD7; BAZ1A; SUZ12; JUP; ELF1; PCGF2; BCL6; CCNE1; ZNF512B; RLF; YEATS2; TRIM28; SERTAD2; MAGED1; MBD2; FOXO1; SP3; UBE2I; ZNF331; ETS2; ETV1; ESR1; BCL11A; NFKB1; CEBPB; TBX2; ISL1; NKX2-1; ZNF423; KAT6A; KDM5D; HMBOX1; BCL3; NR2F2; DACH1; TOB1; BASP1; CRK; PUF60
Down-regulation	55	NKX2-2; SOX10; MAF; MED7; SSX1; E2F3; TAF1A; SATB2; CHD7; FOXC1; EED; STAT1; HLTF; ZNF426; CREM; PPARGC1A; HAND1; WWTR1; MAFB; ARL2BP; CHD4; TRIP6; EGR2; IRF7; NFIB; EN1; LIN28A; STAT4; SMARCD3; RAN; BHLHE41; TRPS1; CBX6; SNAI2; MYCN; ARNTL2; WT1; NR2F1; TXNIP; HTATIP2; HMGN3; ATF3; ID4; ZIC1; CD3D; RXRA; BBX; ZFPM2; ZEB1; MYRF; AHR; RELB; SSBP2; PPARG; E2F2