Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID14613	Osimertinib	GSE70138	HUVEC	Human	24h	3.33uM	EID0045

Response Information :

Types	Number	Response transcription factors
Up-regulation	60	PURA; BRWD1; NFATC3; EMX2; MEF2D; NR0B1; MNAT1; TCF15; NR3C1; BAZ1A; PCGF2; HDAC7; ZNF205; JUND; CHD9; NCOA4; HIC2; RCOR1; RFX7; MGA; PBX2; ZNF423; CHD1; CITED2; TAF1D; CDK8; MAGED1; AFF1; NR4A3; CARHSP1; ELF1; TSC22D2; TSC22D1; TBL1X; ASH2L; ZSCAN31; MITF; RBPJ; CEBPB; SMAD6; MYCL; BANP; MNDA; HLX; KAT6A; HMGN3; MAFB; TBX2; CDK7; SMAD7; DACH1; EYA1; KLF6; ATF3; TCF7L2; TFEC; TRIM29; NR2F2; AEBP1; TOX3
Down-regulation	43	TFDP1; PGR; ITGB3BP; RRN3; BLM; VEZF1; SOX10; ATN1; SMARCE1; E2F3; LOXL2; LITAF; IL16; ACTL6A; KLF5; ZIC1; SLC2A4RG; HOXB5; CEBPG; TRPS1; RAD21; PSIP1; MED21; MYBL1; TRIM22; BIRC2; STAT1; CREB3L1; SPDEF; IRF7; DNMT3B; TWIST1; MYB; KLF10; WWC1; HEY1; ZEB1; HMGB2; MEIS2; TOX; HOXB6; SSBP2; RELB