Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID14604	Motesanib	GSE70138	HUVEC	Human	24h	0.12uM	EID0045

Response Information :

Types	Number	Response transcription factors
Up-regulation	96	MEF2C; MED13; TFAP2A; ZBTB24; ATF4; ETV5; DLX2; MTDH; ZNF589; NFE2L2; MBD4; TAF9; CNOT3; SHOX2; CCNC; HHEX; NCOA2; SUZ12; ISL1; SOX10; FOXE1; DEK; NKX2-1; ZBTB16; NFE2L3; MED4; RFC1; TGFB1; TRIM24; AATF; DLX5; TP63; ZNF536; RNF6; NFKB1; PRMT2; CBFB; CBX7; NCOR2; ELF1; RBBP5; CREB5; MBD2; POU2AF1; RELB; HNRNPD; HMGA1; FOXG1; CERS4; IRF2; MAFB; GTF3A; ZFHX4; TCF4; ST18; BRD7; HOXB7; E2F8; ZSCAN31; TDP2; LHX2; NFAT5; SPIB; BHLHE41; CBX6; SMAD2; BCL3; TFEB; YWHAB; CREBL2; PRKDC; FOXC1; SOX9; TBX3; NR1D2; KLF5; EGR3; TFAP2C; FOXJ3; ZHX2; BMI1; ZNF532; HMGN3; CAMTA1; ID4; CEBPB; MYRF; SMAD7; SOX11; PAX5; ERG; RBPMS; PSIP1; HLF; CRK; PUF60
Down-regulation	81	TP53; MTA1; NCOA1; WT1; MEIS1; ZNF8; NFE2; EMX2; PGR; SIX2; ZNF562; ZNF426; WDR77; ZMYND8; HOXA11; SMAD4; NFYB; TEAD4; MXD1; KLF1; MED21; EGR4; TLE1; RBBP7; CCNE1; ZNF22; SSBP3; LMCD1; MED24; SOX17; ZNF266; NCOR1; RREB1; EPAS1; MITF; STAT1; HLX; KDM5D; STAT4; RLF; AR; HDGF; ESR1; ZNF593; ERBB4; MXD4; FOXJ1; KLF10; HMGB3; ZNF331; TOB1; FOXL2; MLXIP; SMAD6; ZNF83; ZNF131; CENPF; ZNF652; TGIF1; PIR; HOXB2; ZFP36L2; SIX1; PBX3; KLF6; EHF; DDIT3; TRIM22; AHR; NRIP1; BASP1; ZNF91; TXNIP; ID1; MEIS2; PEG3; OSR2; ID3; TBX2; SSBP2; TCFL5