Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID14603 Motesanib GSE70138 HUVEC Human 24h 0.37uM EID0045
Types Number Response transcription factors
Up-regulation 41 FOSL1; CDC5L; EMX2; SALL1; ZFHX3; NCOA6; ZNF467; ZNF232; VGLL4; NCOR2; ZNF331; ETV5; HLTF; ZNF217; ZNF281; TAF9B; SOX13; TRIP6; SP3; PCGF2; WWC1; PDLIM1; SMAD2; MTDH; ZIC1; MBD2; ZNF423; FOSL2; IFI16; TBX2; FOXF2; TGFB1; SAP30; NR4A2; MEF2A; SMAD7; TOB1; MED1; MECOM; MAFB; ZFP36L1
Down-regulation 68 RHOA; YBX3; FOXO1; WWP1; PBXIP1; ZBTB43; ZNF135; TSHZ2; TBX10; BNC1; TCEB2; SP140L; CREBL2; CDK8; CDIP1; GFI1; MEOX1; KLF11; NFE2L1; ZNF274; ZNF140; IRF1; BCL11B; ZSCAN31; KLF6; BTG1; TLE4; ZSCAN18; TCF7; BARX2; KLF5; TP63; STAT4; ZEB1; KLF2; NFATC1; SPDEF; HOXB2; HOXB13; HOXC6; CRYM; UBE2I; MEOX2; FOXL2; KLF4; TOX3; ARNTL2; BATF3; CRY1; ZNF131; ETV1; BASP1; ATF3; IRX5; TCF4; ZBTB20; EHF; BCL11A; INSM1; TBX3; ASCL1; ZFP36L2; PAX5; PBX3; POU4F1; NKX3-1; AEBP1; KDM5D