Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID14572 Doramapimod GSE70138 HUVEC Human 24h 1.11uM EID0045
Types Number Response transcription factors
Up-regulation 66 HES1; ZNF432; FOSL1; EGR2; GTF2I; NRBF2; SIAH2; TCF21; CEBPB; SUV39H1; HMGXB4; ZBTB7A; ING2; TAF1; HDAC9; KLF5; ZBTB18; RCOR1; ZNF267; MTDH; MNT; SAP18; CLOCK; ZNF136; MEOX1; UBE2L3; MYBL1; IRF3; ZNF410; TXNIP; MAGED1; NR0B1; NR3C2; KLF10; TP63; URI1; CALR; PHF20; HOXA5; CTNNB1; ELK3; BHLHE41; ETV1; ZNF593; PCGF2; ZEB2; TBX2; CUX2; HMGB3; SAP30; TOB1; MEIS2; PITX1; DACH1; TBL1X; ERBB2; KAT6A; HMGN3; SOX11; NR2F2; PBX3; LITAF; HOXB6; ID4; PSIP1; PUF60
Down-regulation 47 TAL1; IRF7; GATA1; CUX1; TULP4; ZNF195; KLF1; NR4A2; VGLL1; ARNT2; ARID5A; NR4A1; CERS6; LYL1; SPDEF; CBFA2T3; HLTF; EMX2; ZNF415; NFE2; WT1; HMGA1; RYBP; RAN; TFAP2C; HBP1; NFKB1; ZEB1; ZNF239; IRF9; ESR1; AEBP1; MYRF; ERBB4; BRD2; ZNF423; STAT1; CD3D; FOXJ3; ZSCAN18; SMAD6; GATA6; FOSB; ATF3; LEF1; SSBP2; E2F2