Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID14571 Doramapimod GSE70138 HUVEC Human 24h 3.33uM EID0045
Types Number Response transcription factors
Up-regulation 60 FOS; GATA3; HMGA2; MYC; KLF7; IRF6; EGR1; NFATC3; FOXN3; ARID4B; ZBTB16; SMAD4; HBP1; CREBZF; HOXC6; SMARCC2; ETS1; ZSCAN18; NAB2; DAXX; SMAD7; OLIG2; CNOT2; EMX2; TLE4; NCOR2; HMGA1; TP63; PNRC1; HOXA5; BRD7; HDAC5; PAWR; PDLIM1; TAF7; PFDN5; TBX3; MXI1; UBE2B; CTBP2; IFI16; SSBP2; GATA2; SMARCA2; BCL11A; FOXD1; PITX1; ZNF165; OSR2; ZEB1; TGIF1; RBPMS; ARNT2; HTATIP2; PEG3; TSC22D1; PAX6; SOX4; PSIP1; ATF3
Down-regulation 70 CCNA2; MYCBP; HOXA1; LIMD1; CHD1; NR1H2; SFPQ; WDR77; DMTF1; HOXD10; WHSC1; ELF3; TRIM16; TAF9B; SIX1; ABL1; HNRNPD; CCDC59; MNDA; PCGF1; CNOT3; TGIF2; TDRD3; ZNF331; ZNF576; TFAP2C; FUBP1; FOXA2; SSX1; ZNF593; ELF5; RNF141; NR1D2; NR2F6; ETV5; RBM39; TEAD1; ZNF264; ELK3; ZNF512B; CRY1; BMI1; FOXC1; LEF1; HIC2; LOXL2; MED6; SUB1; TFAM; ZNF430; MEOX2; NFIB; NKX2-1; KLF10; EGR2; POU4F1; ZBED2; CITED1; AHR; ASCL1; NRIP1; PIR; KLF2; ZNF652; ID1; ZNF91; SUV39H1; TBX2; TCFL5; NR3C1