Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID14563	Ibrutinib	GSE70138	HUVEC	Human	24h	0.04uM	EID0045

Response Information :

Types	Number	Response transcription factors
Up-regulation	72	IRF6; ZNF586; ZNF264; ZNF587; HDAC3; MBD4; PTTG1; ZNF83; ZNF426; FOXF1; SIAH2; ZNF611; ZNF551; ZNF468; ZNF606; ZNF329; ZNF8; ZSCAN31; ZNF544; ZNF263; NEDD8; HOXC4; TSC22D2; GRHL2; MED23; SMAD5; SUZ12; MAFF; ZNF134; VGLL4; ZNF160; MITF; AHR; SPIB; NR4A1; PURA; TBX3; ZNF665; WWTR1; HMGB3; TRIM29; CTNNB1; ZNF516; BAZ2B; MXI1; UBP1; TXNIP; ZNF211; UBE2B; HEY1; HMGN3; KAT6A; IRX5; TFAP2C; ZSCAN18; MED21; BASP1; PITX1; TSC22D1; KLF10; ETV1; ZBED2; HHEX; NRIP1; ZNF91; MEIS1; TOX; LITAF; TOX3; EHF; KDM5D; PEG3
Down-regulation	70	BRD4; NFIC; SOX9; BMI1; MYBL1; HMG20A; BAZ1B; TCF3; TEAD4; ZBTB16; IFNB1; WDHD1; BIRC2; HOXA10; PRKDC; HSF1; PLAG1; ETV5; COPS5; PBX2; ZNF7; USP21; CUX2; PUF60; CEBPB; RUNX1; IRF9; STAT4; PLAGL1; MSC; ZNF580; RXRA; SOX13; ZNF593; CHD7; KLF2; FOXO1; ELF4; TLE2; WT1; ZNF423; MYRF; ZIC1; STAT1; ZFP36L2; SMAD6; NFE2; TGFB1; LOXL2; HOXB7; SOX11; MNDA; MYB; SAP30; SNAI2; CITED1; SATB2; TCF7L2; TBL1XR1; TWIST1; AEBP1; BCL3; LMCD1; ID4; POU4F1; ZBTB18; SSBP2; TBX2; RELB; TCFL5