Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID14562	Ibrutinib	GSE70138	HUVEC	Human	24h	0.12uM	EID0045

Response Information :

Types	Number	Response transcription factors
Up-regulation	96	MEF2C; LZTS1; POU3F2; NR4A2; CTNNB1; ENO1; FLI1; NR2E1; IRF4; CDK9; PRRX2; ZNF544; ZNF394; CREM; STAT2; SOX17; EGR4; MTDH; ZFPM2; PRPF6; NFYA; TWIST1; ID2; CNOT6; HOXC4; PKNOX2; BHLHE41; LIN28A; FOXG1; ZBTB16; ETV6; GATA6; YWHAB; MAFF; SMAD7; MYF6; MEOX1; AGO2; HMGB2; ZNF415; EGR3; PCGF2; PEG3; E2F5; ZFHX4; ZSCAN18; NLK; MED6; GATA4; ZNF124; KLF10; NR4A3; NPM1; KLF6; POLR2A; ZNF623; PIR; MDM4; CHD7; VGLL4; MYCN; BAZ1A; ID4; NFIB; TTF1; ID3; HOXC10; BARX2; NR3C2; EMX2; FOSL2; SOX10; PRKDC; CBFB; HEY1; ETV1; HOXC6; ZNF331; AEBP1; LMCD1; MEIS2; HOXD1; MXI1; ERG; TCF4; HOXB7; PBX1; MECOM; ZBTB18; POU4F1; HLF; FOXC1; SATB2; KDM5D; PSIP1; PUF60
Down-regulation	65	BRD4; MTA1; AES; NFIC; TRIM33; ZNF444; CUX1; PIAS4; HDAC3; AR; RNF10; PHF2; FOXF1; CARHSP1; PIAS1; SUPT3H; ZNF148; CDK8; LITAF; RLF; SAP18; BASP1; BBX; EP300; NR2F2; TLE4; CDYL; ZMYND8; PAWR; ING2; CREB5; VEZF1; ZFHX3; MAX; HOXB13; CD3D; TBX3; TOX3; NR1H3; IFI16; ZFP36L1; NKX3-1; TFAM; ZNF12; TBL1X; MITF; LOXL2; SUB1; TP63; SPDEF; DACH1; BTG1; EYA1; RBPMS; ZNF91; LEF1; MAFB; TRIM22; ESR1; ZBTB38; TBX2; SSBP2; NR3C1; E2F2; TCFL5