Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID14560	Ibrutinib	GSE70138	HUVEC	Human	24h	1.11uM	EID0045

Response Information :

Types	Number	Response transcription factors
Up-regulation	42	HES1; MED13; BAZ1A; MTF2; PLAGL1; ID4; ZBED2; ENO1; MYF6; CLOCK; IRF8; MAGED1; JAK2; BNC2; MEF2A; MKL2; SSBP2; MED1; EMX2; HEY1; PBX1; FLNA; BHLHE41; SMAD1; TCF4; ZNF83; BCL11A; LMCD1; HLF; ST18; SOX17; FOSL2; WT1; ASCL1; KLF10; ZBTB16; TFEC; INSM1; TXNIP; E2F2; PUF60; PEG3
Down-regulation	64	ZNF768; TAF6; CDX2; ELF3; ARID3B; HOXB7; TFCP2L1; HOXB5; NR3C2; PPARGC1A; KLF13; EHF; WWTR1; KLF5; AES; NR2F1; CHD7; FOXA2; ABL1; ELF5; TLE2; ADNP2; REPIN1; FOXF2; ARID5A; BRD4; STAT1; RFX5; TRAK1; HOXB6; MYBL1; POU2AF1; LPIN2; DNMT3B; ZNF131; MAZ; SUB1; ZEB1; ZNF281; ZNF587; DACH1; ELK3; TRIP6; NFE2L3; HOXB13; MEOX2; NFAT5; KLF4; CREB5; FOSB; LITAF; FOXC1; SMAD7; RUNX3; TBL1X; HOXC10; PSIP1; RBPMS; NR2F2; ZBTB38; SOX11; BASP1; RELB; NR3C1