Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID14559	Ibrutinib	GSE70138	HUVEC	Human	24h	3.33uM	EID0045

Response Information :

Types	Number	Response transcription factors
Up-regulation	111	ZNF611; ZNF160; IKZF1; HOXA1; PKNOX1; PHIP; ZBTB11; ZNF394; ELF2; EMX2; ZSCAN31; HIPK1; ZNF432; MYB; ZNF721; NFATC3; MAGED1; CITED2; HIVEP2; ELK4; FUBP1; ZNF669; SMARCA5; RRN3; CTNNB1; MED6; CREBZF; CDYL; ZNF589; TULP4; PIAS2; ZBTB1; CIITA; CARHSP1; RUNX1; BCLAF1; ING2; HHEX; TCF7; ZZZ3; HOXA4; EHF; ETS2; PLAGL1; ZNF14; KAT2B; OSR2; POLR2A; TERF2; CDX1; AFF1; HOXA5; ZNF423; ZNF665; TCFL5; INSR; ZMYM2; HIC2; LEF1; ZNF536; ERG; KLF4; JUP; SHOX2; FOXJ1; LIN28A; JARID2; URI1; ZMYND8; ZNF217; PAX5; ZNF593; CTBP2; ZNF587; ZNF117; FLNA; TAL1; RCOR1; NANOG; DMTF1; KLF1; MEIS1; TFAP2C; ISL1; HOXB6; IRF4; TSC22D2; HOXD1; NFE2; SSBP2; NKX2-1; ZNF652; SAP30; WWC1; HTATIP2; ZFP36L2; PIR; TFEC; ZNF165; HOXB7; MYCN; TOB1; ASCL1; KLF2; BASP1; ZBTB18; INSM1; KDM5D; TXNIP; RUNX3; CRK
Down-regulation	99	HOXD10; HEY1; NFIB; MED13; SMARCE1; ZNF331; ZNF281; TRIP4; RELA; NR4A2; SMARCD3; BARX1; IRF9; ZNF532; BPTF; ZBTB48; NCOA4; PA2G4; ZFPM2; WWTR1; HMGA1; ZNF467; MMS19; PEG3; SMAD7; TOX; SOHLH2; BTAF1; CHD3; BRD4; SMARCC2; ID3; TRIP6; PKNOX2; HMGB1; ZNF232; FOXG1; CARM1; NCOR2; STAT5A; ZNF148; HOXC10; TRPS1; ZNF22; MECOM; HDGF; RARA; RBFOX2; ARNT2; EPAS1; TCEA2; STAT6; TCF21; TBL1X; ZNF131; SOX13; PITX1; APEX1; RXRA; STAT1; BAZ1A; SATB2; TAF10; BHLHE40; IFI16; PFDN5; FOXO1; MEIS2; SMAD1; MXI1; CBX6; ELK3; SMAD6; SOX11; ZEB1; IRF8; NFATC1; ZNF512B; ZNF83; EGR2; FOXF1; MSX1; EYA1; CALR; MYBL1; ID1; ID4; RBPJ; PSIP1; ERBB2; HDAC9; TRIM22; HOXB2; TRIM29; GTF3A; FOSB; ZBTB38; RELB; NR3C1