Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID14558	Ibrutinib	GSE70138	HUVEC	Human	24h	10uM	EID0045

Response Information :

Types	Number	Response transcription factors
Up-regulation	121	ADRB2; NFKBIA; HES1; SSX1; GATA3; MTF2; HMGA1; REL; IKBKAP; PLAG1; CTNNB1; MED13; EGR1; KDM4A; CERS6; MDM4; TSG101; ATF2; SUPT6H; TAF9; ZNF813; ZNF195; TP53; RFXANK; MYB; BACH2; PHIP; TFE3; REPIN1; ZNF224; PPARG; HIPK1; BCOR; BCL3; TSHZ2; ZNF226; PLAGL2; MNAT1; CALR; TRIM16; RFX7; STAT2; ZNF12; ELF3; MECOM; SOX12; SUMO1; IRF6; PIR; MED14; BPTF; RBBP5; ZNF91; CHD7; ZNF217; JUNB; MAX; ZNF93; SPIB; ZNF136; SMARCA1; ZNF516; ZNF117; TAF10; HDAC4; ZNF665; RELB; BAZ2B; EHMT2; NFKB1; ZSCAN18; SUZ12; E2F5; FOXO1; IRF1; HHEX; ZNF165; PDLIM1; TRAK1; MITF; LMCD1; SOX17; KMT2A; MED6; NAB1; SIX3; RBBP8; ZNF532; ZNF430; DDIT3; NPAS2; TFDP2; AEBP1; SSBP2; NRIP1; DACH1; ZNF239; COPS5; TFAP2C; TCF7L2; JARID2; FOSB; ESR1; BTG1; CITED1; SIX1; ZNF423; IRF7; KAT6A; MED1; BCL6; ERG; OSR2; TRPS1; ETV1; SMAD6; ZNF131; MSX1; FOXG1; LEF1; PUF60
Down-regulation	79	HMGA2; CCNA2; WWTR1; THAP11; PA2G4; RBL2; HNRNPD; BRD3; BNC2; TAF6; ZBTB38; ID4; TOB1; PMF1; TFCP2L1; ASCL1; ZMYND11; ZNF175; CREB3L2; CBFB; ZNF394; CBX7; FOXM1; BIRC2; ARL2BP; MSC; SMAD5; BCLAF1; ZBTB43; CARHSP1; XRCC6; KAT2B; HMGB2; JAK2; HMGB3; STAT4; NFIB; AIP; RORA; ZNF274; CBX5; SKI; KLF9; ZNF148; NR1H2; FLNA; BANP; BHLHE40; VDR; CREBL2; CCNE1; CUX1; CEBPB; MED21; RXRA; PIAS1; NFAT5; SAP30; BMI1; TXNIP; AFF1; MNDA; ZBTB20; TFEC; PBX3; SOX11; ZFP36L1; FOXC1; FOXD1; SUV39H1; KLF2; IRX5; MAFB; MYBL1; HOXB2; BASP1; PSIP1; TCFL5; NR3C1