Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID14531	Bosutinib	GSE70138	HUVEC	Human	24h	1.11uM	EID0045

Response Information :

Types	Number	Response transcription factors
Up-regulation	68	EGR1; GATA3; EMX2; HIVEP2; MEF2C; JUNB; TRIM29; FOS; TXNIP; KLF5; ZNF250; DNAJC1; CSDE1; MYT1L; ZNF34; ST18; RBBP4; RELB; EGR4; MYF6; TP63; BRWD1; EN2; FOXG1; TWIST1; JUP; SPIB; TAF9B; EGR3; BNC2; FLI1; RBM39; ERBB4; TRAK1; WHSC1; TRIM24; CDK2; KLF9; DLX5; PNRC1; WWC1; PTTG1; DEK; KLF11; ZBED2; SHOX2; PSMC3; HDAC9; CREBL2; TDP2; NFKB1; MITF; SOX10; NR4A2; HBP1; JAK2; KAT6A; MXI1; TBX2; PIR; NR4A1; NR2F1; PSIP1; ID1; RBPJ; ZFP36L2; FOSB; HLF
Down-regulation	94	STAT4; HMG20A; BRD4; RNF138; GATAD2A; TFCP2L1; IFI16; CHD9; MED13; ZBTB43; SP3; SIX2; CCDC59; HOXD11; ARID1A; HOXA11; SMARCD1; SMAD1; SMAD2; SMARCC2; TOPORS; ING2; TBL1X; HOXB5; SMAD7; NFIC; BRD2; NFE2; REST; ZNF580; HOXB6; BASP1; ELK3; PAWR; ZNF148; HOXB2; RARA; HOXA10; CBX5; CDK8; BTG1; MSC; PITX2; MEOX1; LPIN2; LYL1; SP140L; KLF1; ZNF12; TGFB1I1; HOXC6; PBXIP1; CBFA2T3; TGIF1; MLXIP; ZBTB20; HOXB7; MYRF; STAT1; NKX3-1; TCF7L2; EYA1; HOXD1; HLTF; HEY2; ETV5; ETS2; SNAI2; FOXC1; ZNF512B; PAX5; SMARCA1; TSC22D2; FOXJ3; CITED1; FOXL2; IRX5; IRF7; POU2AF1; TAF10; ZNF131; ASCL1; HTATIP2; ZFP36L1; EHF; LMCD1; PEG3; NR2F2; SOX11; RBPMS; PPARG; SSBP2; NR3C1; E2F2