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Overview Perturbagen Expression Profiles Transcriptional Responses
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Overview Perturbagen Expression Profiles Transcriptional Responses
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Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID14529 Bosutinib GSE70138 HUVEC Human 24h 10uM EID0045
Types Number Response transcription factors
Up-regulation 134 NKX2-2; TSC22D3; ETS2; PURA; FOXA2; RCOR1; MEF2C; SIRT2; ARID5B; HSF2; FOS; ZFP30; CEBPB; GATA3; ZNF813; ZNF574; ZNF292; MDFI; ERF; SREBF2; BCL11B; ZNF75D; ZNF32; MXI1; SATB1; ZBTB11; BMI1; ZNF337; RUNX1; ZNF768; RFX7; MED13; ARID4A; SFMBT1; FOXN3; TXNIP; MYF6; BRWD1; AIP; RNF141; NR3C1; NR0B2; ZNF184; TRIM24; BACH1; ELF4; SOHLH2; CNOT6; STAT2; ATF2; LIMD1; SIM2; LMCD1; RYBP; KDM5A; MTF1; NR1H2; SMARCA2; HABP4; ZEB2; RXRA; ZNF212; CSDE1; ATF4; ETV5; PROX1; TOX3; IRF3; SETD3; IRF9; ZNF711; ARID4B; PHF1; CLOCK; TSC22D2; ZNF468; MXD1; NFATC3; UBE2B; BCL6; TMF1; UBE2L3; CHD1; KAT8; NFAT5; ZNF593; CREB3L2; SP2; TRIM29; FLI1; TP63; CNOT1; TCF7L2; DLX5; TRIM16; LPIN2; NR1D2; NRBF2; ZNF410; BCOR; NR0B1; HDAC5; GRHL2; ZNF124; NELFB; NKX2-1; ERBB4; KAT6A; JUND; ZBTB18; HDAC9; ZNF131; TOX; ATF3; EGR2; GATA4; NR1H3; ST18; ARNTL2; ASCL1; MYCL; ZNF83; CITED2; TBL1X; MYCN; RBPJ; MECOM; SOX11; ZNF652; TLE1; CRYM; INSM1; NRIP1; KLF2
Down-regulation 137 CREB1; CCNA2; MYBL2; DNAJC2; SMARCC1; HMGA2; VGLL4; USP22; C1QBP; BRD4; FOXE1; PA2G4; FOXM1; HOXA11; MKL2; DNMT1; WWTR1; CHD4; HMGB1; CUX1; MYBBP1A; GMNN; CENPF; HMGA1; FOXO1; NANOG; TRRAP; RERE; KAT7; HEY1; ZNF544; MED24; ING2; BNC2; BRCA1; RORA; ZNF226; HOXB2; SMARCE1; ITGB3BP; HOXD10; TERF1; LOXL2; MMS19; ZFP36L1; BIRC2; RFX5; PPRC1; ONECUT2; KLF9; SALL1; FOXF1; EMX2; RBM39; ZNF274; LIN28A; TAF5; FEZF2; NCOR2; DNMT3B; ENY2; PRKDC; ARNTL; RBBP7; EN1; ZMYND8; PSMC3IP; AR; PBX2; HDGF; MTF2; HOXA10; TCF7; SSBP3; SHOX2; WT1; TRIP6; ESR1; XRCC6; SSRP1; POLR2A; NFE2L3; PUF60; IRF8; HLTF; RLF; KLF1; ZNF587; PPARGC1A; ZNF266; TFAM; PAWR; PTRF; ZEB1; HOXB5; TRPS1; APEX1; NFIX; CITED1; HHEX; SAP30; FOXJ3; BASP1; HOXB6; PBX1; SOX9; CEBPZ; E2F8; TCEA1; RBPMS; SMARCA1; ID3; STAT6; TAL1; OSR2; ZNF721; MYB; HOXB7; ZKSCAN1; SOX13; CREB5; TRIM22; HMGB2; TBX3; SMAD1; SPIB; ERG; ID4; FOXG1; SUV39H1; RUNX3; ZIC1; MEIS2; AEBP1; SSBP2; ZNF586; RELB
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