Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID14509	Tivozanib	GSE70138	HUVEC	Human	24h	10uM	EID0045

Response Information :

Types	Number	Response transcription factors
Up-regulation	80	CEBPD; GATA3; ARID5B; FOXO4; GABPB1; RSF1; BPTF; ADNP; ZNF337; MDM2; EYA2; SOX5; ZNF426; GLI2; NFYB; TEAD3; SSX1; SP110; IRF1; FOXN3; ZNF528; PDLIM1; PHF1; PHOX2B; BRD4; KAT6B; JAK2; JUP; ZNF623; TCEB2; PHF20; PNRC1; GLI3; TDRD3; HOXA5; TCF25; NKX2-2; SOHLH2; MEIS2; STAT1; SHOX2; YBX1; BNC2; GATA6; KLF7; FHL2; CREBL2; ATF3; PBX1; ZKSCAN1; MYCN; ZNF217; DLX5; DLX2; VDR; ELF4; PCGF2; ZNF423; ZNF512B; INSM1; TRIM22; JUND; SOX11; MAFB; FOSB; RFX5; RBPJ; AEBP1; ETV1; HTATIP2; MECOM; ARNT2; CITED2; ZFP36L1; TOX; BTG1; ZFPM2; LITAF; TLE1; SATB2
Down-regulation	61	CCNA2; HMGA2; MYCBP; MYBL2; DNMT1; EZH2; BRCA1; FOXM1; ATF1; C1QBP; RUVBL2; ID1; NFIL3; CAPN15; NFX1; NR1H2; PA2G4; NR1D2; HMGB1; PITX1; FOXJ3; ING3; TEAD4; HMGB2; CUX1; TGFB1; NR4A2; ID3; SALL1; CENPF; ZNF131; PTTG1; TRIM28; TBL1XR1; CALR; CBFB; ELK3; DMTF1; HOXC10; RBBP8; ZBTB20; HEY1; ZNF331; LEF1; CEBPZ; CBX6; SFPQ; NFIB; IRX5; TBX3; HHEX; NKX2-1; HLF; SPIB; ZEB1; KLF2; SUV39H1; HOXB6; FOXG1; SSBP2; PEG3