Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID14459	Osimertinib	GSE70138	HUVEC	Human	24h	0.04uM	EID0044

Response Information :

Types	Number	Response transcription factors
Up-regulation	59	E2F2; AFF1; CARHSP1; SOX15; PPP1R13L; CTBP2; ETV1; DNMT3B; TOX3; MYCL; SSBP2; JAK2; PBRM1; JARID2; PHIP; BCLAF1; AEBP1; RRN3; NR4A3; INSM1; UBE2I; TCF20; ST18; NR4A2; NR4A1; INSR; HOXC6; BHLHE41; UBE2B; MED1; OSR2; CBX7; SOX13; NR1D2; CREBL2; TBL1XR1; ARID5B; SIX3; ID4; PAWR; TXNIP; CITED2; GATA6; LMCD1; KLF2; ASCL1; ERG; NKX2-2; BTG1; MYB; EGR3; KLF4; KLF5; TOB1; PIR; ERBB4; RUNX3; ETS2; BASP1
Down-regulation	60	SMARCA4; ZBED2; SP140; ZFP36L1; COPS5; DDX17; ZFHX4; ZNF512B; BAZ1A; KMT2B; CREB5; FOXK2; BACH2; EYA1; PEG3; ZNF3; POU2F2; BCL3; HEY1; RBBP8; SMARCA1; MAGED1; TBL1X; TRIM24; RBPJ; PFDN5; SMARCD3; HDAC9; PLAGL2; CITED1; YEATS2; RBFOX2; SIX2; DDIT3; MEOX2; NCOA4; ATF4; SALL1; ELK3; GTF3A; TGFB1; ZNF217; ZNF354A; FOXD1; NR3C2; EYA2; POU2AF1; ELF3; RORA; FOXG1; SOX11; NKX3-1; HOXB6; HLF; HOXB2; SOX9; NFATC3; ADRB2; ZNF586; IKZF1