Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID14299	Osimertinib	GSE70138	HUVEC	Human	24h	1.11uM	EID0043

Response Information :

Types	Number	Response transcription factors
Up-regulation	53	E2F2; ADRB2; NHLH2; KLF2; MYF6; STAT5A; NEUROD1; ARID5B; ARNTL2; ZNF529; BANP; ZKSCAN7; SOX17; PIAS1; IRX5; ZNF516; PEG3; ZNF654; ZBTB16; TRIM22; ZFP36L2; NFIC; TMF1; ST18; ZNF165; IKBKAP; ZNF281; IFI16; HOXD1; PAX6; STAT4; ZNF83; INSM1; HMGN3; ERBB2; IRF1; ELF5; JAK2; MEOX2; ZEB1; NR3C1; TP63; ERG; MSX1; PITX1; TXNIP; ZFPM2; HLF; PLAGL1; SIX1; MEIS1; SHOX2; ESR1
Down-regulation	42	SAP18; ARID1A; EED; GTF2I; NCOA1; SREBF1; SMARCC2; MNDA; CBX6; CDC5L; NPAS2; ZNF12; LITAF; ZBTB1; ZNF512B; SP2; SUZ12; TFCP2; KMT2A; TAF9; BTG1; HMGA1; NFE2L3; POU2AF1; CERS6; SAP30; LOXL2; BASP1; HIRA; ZFP36L1; NR2F2; DLX2; PBX1; TLE4; TFAP2C; ID4; MYB; TOX3; PSIP1; MYRF; NFATC3; PPARG