Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID14246	Ibrutinib	GSE70138	HUVEC	Human	24h	10uM	EID0043

Response Information :

Types	Number	Response transcription factors
Up-regulation	47	MTF2; RELB; NFKBIA; IKZF1; RNF10; TP53; BCL3; LDB1; PBXIP1; RLF; FOXO1; TRIM16; IRF4; IL16; TCF7L2; SMAD2; ELF1; MEOX2; INSR; MED13; TAF10; RYBP; LEF1; ERBB4; CTNNB1; TLE4; RBL2; LMCD1; HHEX; TOX; LITAF; ZNF91; NFAT5; STAT1; FOXN3; TGIF1; JARID2; MAGED1; SMARCA2; CHD7; GATA6; MYB; TWIST1; PBX3; ZBTB18; KDM5D; PSIP1
Down-regulation	36	DNMT1; FOXM1; GTF2I; CCNA2; HMGA2; GATAD2A; ACTL6A; YEATS4; TRIB3; MED21; ILF2; HES1; UBE2L3; HEY1; IRF8; TGFB1; EHF; ZFP36L1; E2F8; PTTG1; TBL1XR1; TEAD4; MYBL1; HOXC10; KLF10; ELF5; TOX3; NR2F1; ID1; INSM1; EGR2; ZIC1; NFATC3; SUV39H1; PPARG; NR3C1