Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID14137	Regorafenib	GSE70138	HME1	Human	24h	10uM	EID0117

Response Information :

Types	Number	Response transcription factors
Up-regulation	76	TCEA2; TP53; ARID5A; NKX2-1; FOXO4; HBP1; FOXO3; IRF9; TSC22D3; TWIST1; NFIL3; CBFA2T2; FOXK2; JUP; IRF6; DDIT3; TCF25; MAF; CUX2; ZNF217; ESR1; FOXE1; RELB; PBXIP1; ZFP36L2; SIRT2; NFIB; PNRC1; FOSL2; KLF9; ATF3; DLX5; CAMTA1; OSR2; SLC2A4RG; ZNF423; PCGF2; BAZ2B; SMARCA1; SALL2; CREM; HLF; BACH2; NR4A3; NFAT5; RYBP; MKL2; SHOX2; PIR; TLE1; STAT4; SSX1; TCEB2; MYCN; SREBF1; NFATC3; BHLHE41; HIVEP2; JUND; VGLL4; MEIS2; SOHLH2; RORA; ASCL1; TRPS1; ZIC1; PDLIM1; MYRF; ID4; BCL3; EMX2; HMGB3; IRF7; GATA3; ID3; ARNT2
Down-regulation	84	FOSL1; CCNA2; EGR1; MYCBP; NPM1; BCLAF1; ZBTB11; UBE2L3; POU5F1B; SMARCA4; ZNF274; PAX5; PPRC1; KMT2D; UBE3A; CSDE1; SF1; HES1; BRCA1; RBM39; SFPQ; ZNF146; TRIM25; SIM2; CTR9; TAF9B; IKZF5; SSRP1; PURA; CBX3; MAX; CBFB; C1QBP; TRIM22; ZNF143; FUBP1; NKX3-1; BAZ1A; GATAD2A; FOXF1; MNAT1; BIRC2; YWHAB; RNF6; HNRNPD; LIMD1; ZNF281; TOB1; RNF14; TFCP2L1; KLF10; NFIC; DEK; FOSB; CCNC; REPIN1; MNDA; CNBP; IFI16; CREB3L2; RUNX1; APEX1; MYT1L; PITX1; HMGA1; HDGF; HOXB5; ZNF544; NR4A2; ZNF652; KDM5D; MYBL1; HOXB6; SOX11; FOXF2; TGFB1; ETS1; HMGB2; CITED2; HOXC6; PSIP1; SUV39H1; CREB1; ZNF586