Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID14091	Alectinib	GSE70138	HME1	Human	24h	3.33uM	EID0117

Response Information :

Types	Number	Response transcription factors
Up-regulation	98	CRYM; SP100; CTR9; MDM4; RBBP5; TSG101; CDC5L; SUPT6H; MSX1; NR1I3; ETV5; TRIM25; KDM5D; RREB1; RUNX1; CHD4; KMT2D; TRIM22; RERE; VDR; E4F1; NFIC; STAT2; NR3C1; ZNF212; ZBTB16; GTF2IRD1; RFXANK; ELF3; DNAJC2; KLF13; NR1I2; AEBP1; ZNF148; HMGB1; KLF5; DLX5; THRA; ZNF205; PIAS3; IL16; MDM2; DLX4; AES; GRHL2; ARRB1; MECOM; ZNF430; PRRX1; IRX4; COPS5; CHD8; BHLHE41; THRAP3; NKX2-1; KDM5A; POU4F1; ZNF394; BCLAF1; MNDA; ZNF195; REPIN1; NR1D2; ST18; TDP2; TBX2; HMGN3; SP140L; TFCP2L1; KLF9; PHIP; LEF1; CTNNB1; RBBP8; ZMYND8; SMARCA2; CITED1; ESR1; MYT1L; BRD2; SOX17; IFI16; FOXF2; HDAC4; PPARGC1A; ID1; HEY2; EGR2; ZFPM2; ZNF423; EYA1; MEOX2; ZBTB20; SOX9; TOB1; POU2AF1; KLF2; EGR3
Down-regulation	108	TFAP2A; BTAF1; PHF1; VEZF1; RLF; RUNX3; ATF7IP; MLLT10; PHF2; ZNF302; TOX3; BAZ1A; LMCD1; YBX2; SIM1; BRD7; ZFP36L1; TAF12; KLF11; NFIL3; TAF1D; MEIS2; TADA3; TTF1; ZNF189; AGO2; BCL6; SUPT4H1; ENO1; SRF; ZNF529; CREM; ELF4; INSM1; KDM5C; ZNF292; ZNF83; SREBF2; CBFB; PAWR; DNAJC1; FUBP1; BRWD1; CREBL2; TRIM29; BLZF1; PBX3; ZNF253; CRY1; PRDM10; NELFB; FOXA1; HMBOX1; TWIST1; NFKB1; ALX1; CNOT6; NFYB; ZBTB18; EDF1; JUND; IRF8; BACH1; SHOX2; MED21; PCGF2; ZNF117; NAB1; E2F5; TSC22D2; PITX1; FOXG1; PBX1; PNRC1; ZNF432; NKX2-2; BCL3; ZNF331; DEK; STAT4; SIX2; PLAGL1; NR2F2; SIAH2; MYCN; KLF6; HOXD3; ATF3; MYBL1; NRIP1; RORA; ID4; MYCL; BASP1; HMGB2; SOX10; CITED2; TRPS1; SMARCA1; PTTG1; PEG3; CTBP2; GATA6; MAFB; CREB1; HOXC6; NFATC3; ZNF586