Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID14063	Dabrafenib	GSE70138	HME1	Human	24h	0.37uM	EID0117

Response Information :

Types	Number	Response transcription factors
Up-regulation	86	TRIB3; MEF2C; TBR1; DACH1; ESRRG; TAL1; PIAS2; XBP1; SMAD2; CUX2; ZFPM2; ST18; ZBTB14; ERBB4; RERE; CARF; SIM2; NHLH2; FEZF2; SMAD4; HSF2; SUB1; MYT1L; ZNF135; SSX1; ZFP69B; NFE2; TCEA1; ZNF24; FLI1; NCOR2; STAT2; HIPK3; NR4A2; ZNF217; PRKDC; TAF11; ATF4; HIPK2; HHEX; ZNF302; KLF1; WWC1; ESR1; CREG1; ELF3; ELK3; CBX7; ZNF711; IRF6; ZNF443; ZNF117; ZIC3; ZNF532; SLC2A4RG; ZNF512B; ZNF552; ZIC1; MED1; NFATC3; ZSCAN31; SOX17; EGR3; AHR; FOXG1; SOHLH2; BHLHE41; SMARCA2; HEY2; MECOM; IRF8; IFI16; LEF1; ZBTB20; EHF; KDM5D; ZBED2; EMX2; MNDA; PBX1; MYBL1; TXNIP; NR2F1; ASCL1; PSIP1; ZBTB18
Down-regulation	46	TULP3; RBBP7; CENPF; CCNT1; PBX3; RBM39; TBL1X; CHD4; CAPN15; TLE4; BRD8; PAX5; LITAF; RNF111; GFI1; HDAC1; ZNF263; ZBTB16; NFE2L1; ZNF394; SMAD1; PIAS1; REL; MTA1; MEIS2; PLAGL1; ZNF91; HMGB3; PTTG1; MED21; KLF6; MAGED1; TOB1; RYBP; BRD4; TCF21; PIR; ARID5B; MAF; ZNF652; HOXD1; BCL11A; SPIB; ARNT2; CREB1; ZNF586