Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID14028 Gw-5074 GSE70138 HME1 Human 24h 0.12uM EID0117
Types Number Response transcription factors
Up-regulation 85 PPARG; ZNF83; ELF3; ZNF587; SUB1; MBD4; ZNF329; ZNF614; ZNF211; TAL1; ZNF551; ABL1; KLF1; TFAP2C; NELFB; ZNF264; PBXIP1; ZNF468; MNAT1; NPAT; DDX17; SSX1; ZSCAN18; DLX5; ZNF165; ZNF177; ZNF415; ID1; GATA1; DEAF1; ZNF419; KAT2B; LEF1; ZSCAN31; TAF11; TRIM28; ESR1; CNOT3; MSX1; SMAD7; ZBTB20; CHD7; PAX6; CIZ1; ZNF282; BIRC2; ZNF586; SOX17; ZNF134; TRIP6; TOX3; ZNF304; MNDA; TCEA1; BAZ2B; EGR3; ARID5B; KLF10; OLIG2; NR4A1; CRYM; ZEB1; ZNF721; TCF4; TRPS1; NR4A2; CCNC; FOXF1; DACH1; IRF1; EGR2; EHF; MYCL; ZIC1; MEOX2; ZNF217; ZFP36L1; BASP1; FOSB; ID4; MYCN; MYB; MECOM; POU2AF1; SOX9
Down-regulation 40 CSDE1; AIP; TTF2; SMARCB1; SMAD4; RBM39; ELF4; YEATS2; RNF4; PURA; IFI16; NR1H4; HOXC4; TULP3; ZNF22; GFI1; STAT6; TRIM22; HHEX; PHF20; RNF14; PIAS1; SPIB; RBPJ; BCL11A; ZBTB16; MED1; CD3D; MAFB; PIR; MXI1; TP63; TOB1; WT1; PEG3; CITED2; CREB1; HOXC6; NFATC3; RELB