Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID13907	Regorafenib	GSE70138	HME1	Human	24h	0.37uM	EID0116

Response Information :

Types	Number	Response transcription factors
Up-regulation	100	SMARCC2; ZMIZ2; CALR; UBE2L3; TSC22D2; ARID4B; MAGED1; ZNF195; MED14; RAD21; ZMYND11; ASXL1; FOXG1; POU2F2; MYBL1; ZNF580; LPIN2; BTF3; TOB1; NFATC3; ZNF232; ZNF692; MITF; SPIB; ZNF45; CEBPA; DDX5; ZEB2; ZBED4; ZNF552; PHOX2B; MAZ; NCOR2; URI1; FOXF2; NR3C1; CLOCK; CENPB; LEF1; MED13; SLC2A4RG; FOSB; E2F3; DEAF1; TRIM22; TRPS1; TFAM; TBX3; NR1D2; ZNF281; CBX4; FLNA; HIVEP2; YEATS2; BCOR; ZNF354A; NLK; REPIN1; TAF10; TTF2; ID1; PITX2; LOXL2; CITED2; KLF13; RBBP7; ZFP36L1; BCL3; ID3; POU2AF1; IFI16; MED1; NFAT5; VDR; YBX1; PURA; BAZ1A; SREBF1; SSBP2; ZNF468; ERBB4; KDM5D; VEZF1; HLX; HMGB1; ZBTB18; HMGB3; NKX2-1; SAP30; MAF; CREB1; ZNF107; TOX; ZMYND8; MXI1; NFE2; FOSL2; SOX9; TLE4; TCF4
Down-regulation	78	CREM; TRRAP; JAK2; TTF1; MED24; NR2F1; ZNF134; CREG1; GCM1; FHL5; RNF4; PCGF1; ZNF721; KAT6B; DNAJC2; SATB2; TCF21; MED27; COPS2; MYCN; PDLIM1; SUPT3H; HOXD3; SAFB2; BASP1; ZKSCAN1; DDIT3; IKBKAP; SMARCE1; INSM1; ZNF264; DNAJC1; NKX3-1; MNAT1; HHEX; HOXD1; IRF5; PRRX2; PLAG1; RUNX3; CRY1; PEG3; NR0B1; HMG20B; CBX7; FOXE1; FOXD1; MEIS2; CTNNB1; PITX1; ELK3; THAP10; NKX2-2; NPAS2; ZIC1; CERS6; ZNF430; ZEB1; RNF138; YBX3; NEUROD1; KLF2; ZNF91; FOXF1; ZNF652; ATF3; EHF; PLAGL1; MAFB; ZFPM2; HIRA; HEY1; FOXC1; WWTR1; AEBP1; STAT4; NR4A2; HOXB2