Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID13905	Regorafenib	GSE70138	HME1	Human	24h	3.33uM	EID0116

Response Information :

Types	Number	Response transcription factors
Up-regulation	95	BRD2; NR1H2; TRIM24; CNOT1; TSC22D3; FOXF2; MSX1; TSG101; ELF4; ZNF473; TCFL5; MYT1; BTF3; TDP2; TFDP2; OSR2; ZFPM2; NCOA2; CDYL; TXNIP; ZNF112; ZNF124; NKX2-1; KDM5D; TCF20; TP53; ZNF12; ADNP; IRF7; RREB1; SOX4; LEF1; REPIN1; ZFP36L2; CREB3L1; RSF1; WWTR1; NFAT5; HOXB6; ARID5B; BAZ2B; HMGB3; SOX17; NLK; INSM1; SOX13; ZBTB16; CRY1; ETV5; GATA6; ASCL1; AFF1; VGLL4; BCOR; FOXD1; ZKSCAN1; PMS1; CSDE1; YBX1; LPIN2; CRYM; CREB3L2; MEIS1; TGFB1I1; FOXA1; TWIST1; NEUROD1; TCEB2; ESR1; FOXC1; KLF13; ZBED1; DBP; ZNF217; MITF; TBX3; IRF1; NR1D2; NR2F1; MXI1; ZBTB18; LITAF; DLX2; NR1H3; ZNF423; ATF3; DACH1; BTG1; HOXA5; PBX3; IFI16; RERE; ERBB2; PDLIM1; MECOM
Down-regulation	106	BRPF1; CBX5; CCNA2; CEBPG; IKZF5; NELFB; CREBZF; MAX; SCAND1; CCDC59; KLF7; IRF8; ZNF384; TCF7L2; KMT2A; SAP18; ZBTB40; ZNF160; PUF60; ZNF146; BASP1; TFDP1; ZNF562; ZFHX4; PEX2; ZNF721; ARNTL; NFIB; MED21; SAP30; NAB2; CCNC; BTAF1; TAF11; PAX5; AGO2; FOXM1; FOXK2; MED27; RAD21; COPS2; CIZ1; MEF2A; TRAK1; SFPQ; TRIM29; JAK2; HEY2; ATF7IP; TFAP2C; CITED2; PAXBP1; C1QBP; BMI1; TCF7; HMBOX1; ACTL6A; LOXL2; FUBP1; TCEA1; TLE1; HES1; ARNT2; HTATIP2; ZNF593; PPARG; SSX1; APEX1; NPAS2; ZNF273; PPP1R13L; KLF9; ZNF611; CEBPZ; DMTF1; MTDH; TRIP6; ZNF432; NKX2-2; ZNF117; HIPK3; TLE4; CENPF; NR0B1; NR3C1; HIRA; HMGB2; GTF2I; FOXG1; MYCL; ZEB2; ZNF91; ZBTB20; HOXC10; TOB1; MNDA; MTA1; PLAGL1; RORA; EMX2; TRPS1; ZNF652; ZFP36L1; THAP11; CREB1; EGR3