Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID13904	Regorafenib	GSE70138	HME1	Human	24h	10uM	EID0116

Response Information :

Types	Number	Response transcription factors
Up-regulation	88	TSC22D3; TCEA2; HDAC6; ARNT2; CSDC2; FOXO3; SOX4; NFIL3; TP53; IRF9; ARID5B; ZMYM2; CUX2; CREB3; TWIST1; TFAP2A; HBP1; CREBL2; SP100; CARHSP1; TAL1; BACH2; ZNF24; ELF4; INSM1; PQBP1; ZNF91; SP110; CREB5; RBFOX2; ZNF85; KLF11; ZNF43; KLF1; ZFP36L1; ATF4; ZNF93; PNRC1; TBL1X; PBXIP1; TGFB1I1; PCGF2; VPS72; LITAF; ZNF224; RNF10; IRF7; TRIB3; BRD4; AES; MXI1; BTG1; TXNIP; NKX3-1; ZNF580; TFDP2; ZNF12; PBX1; ID3; MKL2; ASCL1; LEF1; DLX5; POU2AF1; SOX13; FOXO1; FLNA; JUND; DDIT3; TLE1; MITF; MECOM; IRF1; IFI16; CRYM; TOX; MAF; SALL1; BCL11A; PSIP1; MEIS1; PDLIM1; ESR1; SIM2; PAX5; CREB1; PIR; THAP11
Down-regulation	98	FOSL1; MYC; RUVBL2; MYCBP; EGR1; CDK2; TFDP1; TCERG1; BRCA1; BCLAF1; YAP1; ELK3; ZBTB20; TAF1D; PPRC1; EZH2; NPM1; SFPQ; AGO2; MED17; TRRAP; ZNF443; HES1; CCNA2; BMI1; CTR9; CBFB; MNAT1; IRX5; TRIM27; ZNF189; ZMYND11; SMAD5; FOXD1; CLOCK; PA2G4; C1QBP; CREB3L2; RCOR1; WDR77; PHIP; BAZ2B; GCFC2; DDX5; BAZ1A; TMF1; ENO1; PMS1; DMTF1; DLX2; TAF9B; FOSB; HNRNPD; RNF141; HLTF; RBPMS; CUX1; RBL1; NPAT; DNMT3B; HIPK3; PRKDC; EGR3; AHR; PURA; NR4A2; SATB2; GATAD2A; CEBPZ; SIX1; POLR2A; ZBED2; GTF2I; HDAC1; MLXIP; ZBTB18; KLF2; JARID2; FOXC1; NCOA1; SUV39H1; AFF1; TFAP2C; RUNX3; PLAGL1; SMARCA2; MYB; CHD7; HMGB2; ID1; RERE; NR3C1; WWTR1; TBX3; SOX9; HOXC6; PEG3; TCFL5