Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID13861	Alectinib	GSE70138	HME1	Human	24h	0.12uM	EID0116

Response Information :

Types	Number	Response transcription factors
Up-regulation	107	STAT5B; MTF2; NR1H2; FOSB; CBX5; ZBTB17; YBX2; TFDP2; ETV1; ZNF562; PAX6; RAD21; TCF4; PTRF; CCNT1; HSBP1; ARNTL; CDK8; ID1; DDX5; BNC1; EPAS1; ARID5B; SMAD5; ZNF160; CITED2; CCNC; NFIC; SMARCD3; ZNF611; ING2; ZXDC; TGFB1I1; GATA1; CNOT6; RBPMS; TCF3; PPARGC1A; TCF7L1; FOXF1; JUNB; TFE3; TCF20; ID3; ARL2BP; CLOCK; ZSCAN31; LIN28A; CITED1; DNMT3B; ZBTB43; RAN; ZNF665; SOX11; FOXF2; TLE2; NFIB; NANOG; HEY1; ZNF211; CNBP; ZEB1; SPEN; PNRC1; HOXA1; DACH1; BTG1; CD3D; ZBTB20; ZNF721; BCOR; ENO1; MXD1; CEBPZ; E2F5; YBX1; AES; ZNF264; TP63; CBFA2T3; ZSCAN18; PITX1; INSM1; NR4A1; SSX1; SMARCA1; CENPF; FOS; ZNF83; REPIN1; TBX3; CREB1; NCOA1; ERG; CHD7; PEG3; WWTR1; EYA1; TGFB1; BCL11B; HOXA5; TLE4; NR4A2; MEIS1; SOX9; THAP11; MYB
Down-regulation	91	CREG1; DPF2; SP3; MED6; TCF25; NKRF; CERS6; AATF; FOXD1; ZNF217; HSF2; ETV5; SAP30; BRWD1; TOX3; ERCC3; MNX1; RUNX1; IKBKAP; USF2; TTF1; MED17; IRF9; PQBP1; AIP; HOXB6; ELF4; MED23; MAFB; DNAJC2; MEF2D; NKX2-2; BCL6; ZIC1; HOXD10; PRPF6; ZNF267; CRY1; CDC5L; USP16; HDAC9; TBX2; PATZ1; APEX1; BPTF; THAP10; CUX2; SATB2; OLIG2; TRIM32; IRF4; NCOR2; ZNF423; CSDE1; HMGA1; ARID4A; PHF20; ZBTB1; MAGED1; EMX2; SMARCA2; MTDH; NRIP1; RBM39; TFAP2C; SOX13; CRYM; MYRF; ZNF32; ELK3; HOXB2; MYBL1; PBX1; EHF; PIR; GATA6; LMCD1; RNF138; WT1; HOXB7; RUNX3; MXI1; VGLL4; EGR3; HOXC10; MNDA; HOXA10; HHEX; ESR1; TCFL5; IKZF1