Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID13836	Vx-745	GSE70138	HME1	Human	24h	0.37uM	EID0116

Response Information :

Types	Number	Response transcription factors
Up-regulation	85	MTF2; ZNF248; PBX2; CNOT1; MAZ; ZNF14; NR2F1; NR1D2; TWIST1; CDX2; NFIC; TAL1; RFX5; KDM5D; ZSCAN18; MECOM; ZSCAN31; CARHSP1; HOXD3; CIR1; ZNF217; TAF7; MXD4; SOX17; MYT1; UBE2B; HOXB13; ZBTB20; NR4A1; TLE2; RARA; MKL2; ATN1; TERF2; MYF6; AES; CBFB; INSR; MXD1; NR3C2; SMAD6; RRN3; CARM1; MXI1; CERS6; PIAS3; CBX7; LEF1; TRIM16; ZNF148; CRYM; YWHAB; ETV5; DACH1; JUP; FOSL2; ATF3; SMAD7; NPAS2; BCL3; TGFB1; ZMYND8; FOXJ3; ERBB4; EGR2; ID3; ELF3; BHLHE41; ZBTB38; ZBTB18; ID1; PITX2; ERG; POU2AF1; HEY1; HOXD1; ID4; EYA1; SMAD1; CTBP2; ASCL1; SSBP2; LITAF; TXNIP; NR4A2
Down-regulation	79	MLLT10; JAK2; NFYB; ELF5; SAP18; NFIB; KLF11; BAZ1A; FOXN2; PAWR; PEG3; BASP1; ZFX; NFATC4; RBPMS; GFI1B; FOSB; YAF2; SAP30; NAB1; ZBED2; KAT2B; HOXC6; IRF8; TRPS1; NFKB1; SPIB; DDIT3; CEBPZ; HOXB5; MED21; ZNF146; NRBF2; DNMT3B; PHF20; ZNF85; HDAC9; SCAND1; TAF12; SIAH2; RUNX1; BTG1; KLF10; TRIM22; OLIG2; SMAD4; FOXL2; ZNF165; CITED2; ZNF281; ZNF22; PMS1; MYBL1; REL; KLF4; TTF2; SSX1; AHR; LMCD1; HIPK3; RUNX3; CD3D; YEATS4; HOXB6; KLF6; OSR2; TOX3; PAX5; IRX5; TRIM29; TGIF1; EDF1; ZIC1; ZEB2; PBX1; WWTR1; MEIS2; CREB1; EHF