Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID13832	Dabrafenib	GSE70138	HME1	Human	24h	0.04uM	EID0116

Response Information :

Types	Number	Response transcription factors
Up-regulation	54	HR; ELF1; ZMIZ2; SAP18; ID1; ID2; KLF5; UBP1; ZBTB14; OVOL2; ZNF24; BCLAF1; MED1; HES1; ZNF552; NAB1; PKNOX1; BTG1; ERBB4; ETS2; TCF20; AFF1; KLF11; HMGA1; ZNF124; SOX17; CBX3; ZNF532; HOXB7; ATF3; ELF3; STAT1; ZBTB18; MITF; NKX2-1; RUNX1; JUP; ZBED1; RBPMS; MAFB; JARID2; MYCL; ZNF217; ATF4; HDAC9; CRYM; PITX2; TXNIP; HOXC6; TBX3; MYCN; MECOM; CITED2; NRIP1
Down-regulation	92	EYA1; PDLIM1; MAFG; CREG1; COPS5; NR2F1; INSM1; BCL11A; PEG3; SIX1; POU4F1; HMGB2; TLE1; ZNF160; DNAJC2; IKBKAP; CREBZF; MAF; ZNF652; NR0B1; ARID5B; POU2AF1; TFEB; NR2F2; ZBTB20; E2F5; HOXC4; FOXO4; ZFHX4; KAT6B; HEY1; COPS2; ZNF721; PIAS1; TSC22D2; MKL2; SIX2; MYT1L; MEIS2; ZNF611; TCF4; WWP1; PLAGL1; MED24; PAX6; LMCD1; RNF111; TCF7; ZKSCAN1; PTTG1; ZNF44; MEF2A; TGFB1I1; MTDH; KLF2; GTF2IRD1; CBFA2T3; HIPK3; SAP30; SATB1; HLF; PAX5; MAGED1; PITX1; MYRF; CUX2; ZMYND8; BACH2; SOX11; GATA3; YBX3; SMAD1; SIM2; THAP11; CHD7; TOX3; SMAD6; TWIST1; MYBL1; WWTR1; HIRA; CTBP2; NR1D2; ZNF331; ZNF91; ZNF512B; SOX9; RORA; WT1; DACH1; NR3C1; LEF1