Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID13830	Dabrafenib	GSE70138	HME1	Human	24h	0.37uM	EID0116

Response Information :

Types	Number	Response transcription factors
Up-regulation	92	ST18; INSM1; CREM; KDM5A; TDP2; ARID5B; FOXG1; NFATC4; ZSCAN18; ZNF423; ARNT2; NR4A3; NKX2-2; ZNF345; ING4; TLE2; HMGA1; CHD3; ZNF711; VGLL1; FOXA1; TWIST1; NEUROD1; TRIM24; EP300; ELF4; TULP3; HIVEP1; ZIC1; FOXM1; ZKSCAN1; ZNF652; GFI1B; MAFG; CRYM; NRBF2; CRY1; ILF2; ATF4; NFIB; ZNF529; HLF; VPS72; HIRA; TTF2; PFDN5; ID1; BCOR; SOX11; PCGF2; ZNF394; TSC22D1; MECP2; AES; ATF3; IRF7; ELF5; MEIS1; NR1H2; CUX1; ZFPM2; AHR; NFE2; LYL1; RBBP4; SMARCA1; ZNF131; ZNF32; ABL1; ZBTB16; BACH2; SREBF1; TRPS1; ZBED1; CUX2; FOXF1; DDIT3; ZNF217; HOXB2; TOX3; HDAC9; PEG3; RBPMS; TGFB1; MEOX2; FLNA; EHF; SOX17; HHEX; ID4; ERBB2; MECOM
Down-regulation	85	TSC22D2; CCNT1; TCF7L2; XBP1; MDM2; HOXC6; IKZF5; APEX1; CIZ1; SP140L; UBTF; E2F6; USP16; PMS1; ARNTL; IFI16; ZBTB1; CHD7; ADNP2; SERTAD2; NR2F2; PRRX1; TFCP2L1; RBM14; SSRP1; ING3; ZNF12; PRKDC; KLF11; SFMBT1; PREB; HMGN3; FOXL2; MBD2; PAX5; BHLHE41; REPIN1; CHD8; GTF3A; CENPF; ZBTB38; THAP10; PAWR; NFYC; CREB3L1; ZNF267; PURA; RBM39; SMAD2; NRIP1; TFDP2; BTG1; PTTG1; TBL1X; MAF; MYBL1; TRIM22; CEBPZ; NR1D2; POU2AF1; TRIP6; MXI1; HMGB2; PUF60; BCL3; SATB1; ELK3; LOXL2; RXRA; IRF9; TCF21; ASCL1; MAFB; CREB1; SMAD1; MYCN; GATA6; ID3; WT1; ZNF91; DACH1; PDLIM1; E2F2; MEF2C; NFATC3