Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID13829	Dabrafenib	GSE70138	HME1	Human	24h	1.11uM	EID0116

Response Information :

Types	Number	Response transcription factors
Up-regulation	110	ZNF589; TBX2; GATA3; ZNF232; ZEB2; XBP1; ZNF266; ARID4B; CALR; RING1; BTF3; ZNF45; HOXC4; NR2F1; ZHX2; ISL1; MBD4; ZNF506; BRD8; AES; BAZ1A; PHIP; CSDE1; MEIS1; ZNF83; PEG3; PTRF; SPIB; SMAD4; BTG1; TAF1D; MED17; ARNTL2; ZNF573; EPAS1; BRD2; LMCD1; MYBL1; BTAF1; HIVEP1; MAZ; YWHAB; AR; ZNF430; TTF2; RBBP5; ZNF426; NCOA4; FOSB; ESR1; GTF2I; SOX13; HIPK1; MAF; JARID2; FLNA; ZNF529; ARID5B; ZSCAN31; DDX5; ZNF184; HIVEP2; LPIN2; TLE4; MAML1; EDF1; TRIM16; BCL3; ETS2; GATA4; RBM39; CHD9; PITX1; LZTS1; ZKSCAN1; ZSCAN18; FOXF1; KLF4; NR3C1; TCF21; STAT6; ZNF117; LITAF; ATF4; CD3D; ADRB2; TCEA1; IRF9; FLI1; SMARCA2; HLX; LEF1; ZNF32; PBX1; ZBED2; NR1H3; PBX3; TOX3; TFAP2C; AHR; EHF; NR2F2; DLX2; ID1; PTTG1; ZNF512B; STAT4; HOXC6; GATA6; THAP11
Down-regulation	67	RNF6; ITGB3BP; PAX6; MKL2; HOXA7; ETV4; CREG1; ING2; HTATIP2; HOXA1; SAP130; SIX3; ST18; SUB1; RBBP4; DNMT3B; KLF7; SCMH1; IRF7; NFAT5; RBBP7; FOXM1; GTF2IRD1; KLF5; KAT6B; SETD3; HIRA; SMAD3; ANKRD1; EED; IRF8; SSX1; ZBTB38; BCL10; ZIC1; CUX2; ELK3; TFCP2L1; MYCL; CDK8; NR0B1; TERF2; SATB1; CHD8; CBFB; MAFF; ATF3; FOXO1; HDAC9; ID2; SMARCA5; ZBED1; FOXN3; NR3C2; GTF3A; CRYM; TRIM29; EYA1; YEATS4; ZNF423; FOXC1; HOXA10; SOX9; BHLHE41; DACH1; ZFP36L2; KDM5D