Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID13828	Dabrafenib	GSE70138	HME1	Human	24h	3.33uM	EID0116

Response Information :

Types	Number	Response transcription factors
Up-regulation	72	CALR; FLI1; SOHLH2; HES1; SRY; NKRF; XBP1; CREM; HOXB13; CSDE1; TTF1; ING3; CITED1; HOXD3; HOXD11; ELF4; HOXD10; CHD3; NR4A3; SAP30; OVOL2; MEOX1; ARID5B; VGLL4; HOXB2; ZFHX3; HOXB6; ZNF124; TFAM; EGR4; FOXF1; LIN28A; RNF10; SSX1; BBX; NANOG; ZNF467; SND1; MEOX2; ASCL1; ISL1; HIPK2; PBX1; OSR2; FOXG1; HOXD1; HMGB3; IRF8; IRF9; ARNT2; ZBED2; CRYM; PEG3; SIM2; STAT6; MITF; NPAS2; NKX2-2; MYCN; RERE; HLF; WT1; IFI16; PSIP1; EGR2; POU2AF1; NR2F2; CREB1; NR1D2; STAT4; TRIM22; ERBB2
Down-regulation	71	RHOA; ZNF131; MTF2; MED4; ZNF24; FUBP1; ZNF45; SERTAD2; HDAC3; CRY1; RUVBL2; FOSB; ZBTB18; RRN3; BCLAF1; CHD9; ATF2; KLF7; CREBZF; HMG20A; PHF20; TRIP6; NOC2L; NR2C1; PURA; BMI1; ZNF623; CCNC; YWHAB; SMAD3; NFIB; UBE2I; TP63; CHD8; CNBP; TCF4; CDK8; HOXA1; SKI; PRKDC; WNT4; MYBL1; NR3C2; MEF2A; MLXIP; ZNF302; WWTR1; RFX5; CEBPZ; FOXN3; CBX7; RUNX1; CHD7; PAX5; TGFB1I1; HMBOX1; TBL1XR1; RORA; KLF6; MYB; IRX5; RUNX3; ZNF107; AEBP1; TBX3; NR2F6; KLF2; FOXC1; ID4; DACH1; TCFL5