Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID13827	Dabrafenib	GSE70138	HME1	Human	24h	10uM	EID0116

Response Information :

Types	Number	Response transcription factors
Up-regulation	65	CSDC2; TSC22D3; PCBD1; ZNF248; ING4; CEBPD; TP53; NR2F1; HOXD3; NKX3-1; PBX1; NFIL3; PBX3; TRIM29; ZSCAN31; PITX1; E2F5; PEG3; LMCD1; URI1; TRIM16; MNAT1; CALR; HOXB13; TRIM24; MED23; MED21; PAX6; BCL11A; GATA6; ARNT2; HOXD1; C1QBP; TCF21; NFIB; ZNF415; TRPS1; TBL1XR1; SOX9; ZHX2; FLNA; WT1; SSBP2; AES; MEIS1; PIR; ASCL1; MEIS2; ZNF165; HEY1; BHLHE41; TOX3; FOXF1; SREBF1; BTG1; LITAF; TBX3; APEX1; TLE4; MNDA; NR2F6; TRIM22; WWTR1; TRIB3; THAP11
Down-regulation	69	FOSL1; HMGA2; KLF9; FOXD1; EGR1; EGR3; HOXA1; MED17; PCGF3; ARID4B; ZBTB20; ELK3; EGR2; HIC2; BCL10; EGR4; TRRAP; NPAT; MSX1; HOXB7; LPIN2; RNF141; KLF10; MDM4; HOXA11; VEZF1; BAZ1B; ARNTL2; MAFB; NCOA2; PRRX1; ZNF264; MAFF; MKL2; BMI1; LOXL2; NFAT5; NR1D2; KLF11; SNAI1; ID1; ING3; SFPQ; HIPK1; ZBTB38; ZNF532; SMAD7; MITF; BCL11B; ZNF281; SMAD2; HOXA10; TCF7L2; FLI1; DLX5; EYA2; FOS; TBX2; KLF13; ID3; TGFB1; RUNX3; KDM5D; NR3C1; NR4A2; BASP1; CREB1; IKZF1; NFATC3