Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID13780 Tak-715 GSE70138 HME1 Human 24h 3.33uM EID0116
Types Number Response transcription factors
Up-regulation 166 ING2; HOXC8; C1D; POU6F1; NEUROD2; NEUROD6; ZNF248; ZNF253; TUB; TRIM24; ETV3; ZNF276; FOXP3; MED4; ZNF711; ZNF506; JAK2; MYF6; MED25; FOSB; CBX7; GATA4; ZBTB18; CSDC2; CREB5; TRIP4; ZNF292; CCNC; MEF2C; NFIC; HEYL; ARRB1; ZIM2; RXRG; ZNF189; ZNF160; TBX6; SRY; ACTL6B; RSF1; PRDM2; FOXE1; ZMIZ2; HOXC10; PRDM14; HOXC11; HDAC5; ZNF667; ZNF266; MED20; POU2F3; FUBP1; TCF4; CRYM; EGR3; RNF111; ZNF443; FLI1; MED7; ADNP; MED17; NHLH1; HMG20A; FOXL2; ZNF175; ZNF529; HNF1B; NR3C2; ZNF14; THRA; SATB1; ZNF611; IRX4; TFEC; UBE2L3; ARNTL; NFIX; TAF11; NR2E1; MYT1L; RNF6; RARB; ZNF532; DEAF1; ETS2; TFCP2L1; NR4A3; NR4A1; SAP30; RCOR3; UBE3A; REPIN1; NANOG; TOB1; EP300; PPARGC1A; SCAI; AR; PEG3; NPAT; FOXO4; BCL6; ZBTB43; BARX2; HOXC6; MKL2; TBX3; GRHL2; MAFB; ZSCAN16; LPIN2; ZBTB20; HOXB5; BCL11A; PAWR; BCL11B; ZNF652; PNRC1; KLF10; ARID4A; NKX2-1; CUX1; LHX6; TWIST1; ZNF44; DACH1; TRPS1; NR4A2; CREB3L2; BNC2; TRIM32; MNT; ZNF721; CBX3; PRRX1; CAMTA1; ZFP36L1; TERF2; CERS6; SIM2; NFATC1; CD3D; TOX3; ZNF331; ESR1; AFF1; TXNIP; TBL1XR1; ARNT2; TCF7L2; HMGB2; WT1; EYA1; HMBOX1; ZNF430; ZFPM2; ERBB4; HLF; SMARCA1; TCF21; ZIC1; IRX5; STAT4; CITED2; MYB; THAP11
Down-regulation 107 NFKBIA; ETS1; SNAI2; PUF60; ZNF24; MNAT1; FOXJ3; RYBP; HMGA1; KAT6A; CEBPZ; NRIP1; SF1; DMTF1; TAF9B; CEBPG; SMARCD2; NCOA6; TAF10; SCAND1; FOXN2; POU2F1; STAT3; SMARCB1; SIX1; TCEA1; ZNF232; OSR2; ETV5; BASP1; YBX1; SMARCC1; MTA1; PRPF6; IRF1; ATF4; BACH2; ZNF23; RBM39; ZNF557; PIR; SUPT5H; CHD7; CSDE1; ARID1A; MED27; ST18; SOX4; MDM4; GTF3A; FOXA2; NFYC; BCL3; PA2G4; ATF5; DDIT3; E2F5; EHF; EHMT2; FOXC1; MECP2; TRAK1; DNAJC1; RELA; MTDH; KAT2B; EYA2; RUNX3; TADA3; FOXA1; FOXD1; VPS72; SATB2; LITAF; TGFB1; LMCD1; ZNF580; APEX1; CARM1; MBD2; AEBP1; SSBP2; TGFB1I1; PFDN5; C1QBP; HDAC1; NPAS2; FOXN3; PURA; TCF7L1; SOX13; LOXL2; FLNA; RBPJ; EMX2; SALL1; NR2F2; PAX5; RBPMS; POU2AF1; MXI1; PBX1; MEIS1; HOXB7; MECOM; CREB1; HMG20B