Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID13736	Azd-7762	GSE70138	HME1	Human	24h	0.04uM	EID0116

Response Information :

Types	Number	Response transcription factors
Up-regulation	125	FOSB; MSX1; NFX1; WHSC1; ZBTB48; ZNF232; ZSCAN9; KAT2B; NCOA6; SERTAD2; TRIM24; ZHX2; E2F5; ZNF189; EHMT2; CREB3; ARID5A; REPIN1; TAF9; LPIN2; NHLH1; TOX3; MED16; EP400; TAF5; ZNF329; HDAC5; BTF3; RREB1; PHF8; TRIM27; TGIF2; ZMIZ2; NFE2; ZXDC; TAF4; TDP2; RUNX1; KLF1; ZNF3; MYB; CNOT6; SP2; RAN; BAZ1B; MED12; SOX11; YBX1; SETDB1; CBFA2T3; ZNF516; CREM; EYA1; ZSCAN18; ZSCAN16; SIX1; HMGA1; MECOM; HEY2; TFDP2; MAML1; TRAK1; WWP1; NCOA4; RBPJ; TAF12; ZNF580; ZNF83; HSBP1; PIR; TAF11; PURA; NR4A2; PATZ1; IFI16; SPEN; CDK8; NCOR2; BACH2; OLIG2; ZNF43; ZNF394; TAL1; RELA; KDM5D; BCL11A; MYCL; PSMC3; CTNNB1; NFYC; AEBP1; AES; TCF7; ASCL1; EDF1; IRF1; CHD7; DDIT3; ZNF165; ZBTB18; ZFP36L2; HOXC10; TCF7L1; KLF6; ZEB1; FOXO1; MXI1; ZNF32; POU2AF1; ZMYND8; SALL2; HEY1; CREB1; AFF1; EGR2; ARNT2; INSR; MNDA; ZNF331; TRIB3; THAP11; SOX9; CD3D; MAF; LITAF
Down-regulation	90	HIF1A; ADRB2; ARID4B; ATF5; TEAD1; JUP; SMAD3; MDM2; TP63; UBE2I; TRIM29; MLLT10; PUF60; NFAT5; SMAD5; CEBPD; KLF7; STAT3; PTRF; POU4F1; ZMYND11; CREB5; THAP4; MAFB; AFF4; GABPA; ZNF12; CAPN15; HOXA7; KAT2A; ZNF267; KLF11; ELK3; NCOR1; PRKDC; PHIP; TOX; ZBTB1; MED21; C1QBP; RRN3; ELF2; CNOT2; TAF9B; RCOR1; CARHSP1; ZEB2; TCEA1; BNC2; KLF5; IRF6; WWC1; PPARGC1A; PLAGL1; ZBTB43; SIN3B; BBX; ERBB2; AR; NFIB; BATF; POLR2A; HIPK3; PITX2; ZNF467; PPP1R13L; ANKRD1; TOB1; HMGN3; MITF; NR1D2; PDLIM1; NCOA2; CERS6; FOXD1; PAWR; JUND; KLF2; TGIF1; LMCD1; GATA6; SMAD6; FOSL2; HOXC6; SREBF1; EMX2; ERBB4; EGR3; NR2F6; WT1