Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID13362	Jq1-(+)	GSE70138	HME1	Human	24h	1.11uM	EID0081

Response Information :

Types	Number	Response transcription factors
Up-regulation	91	TFAP2A; SSBP2; ABL1; DRAP1; HDAC5; CBFA2T3; PBXIP1; NR4A1; INSM1; MXD4; E2F2; PNRC1; SOX15; MYT1; PIAS1; ZNF394; ASCL1; HMBOX1; NR4A3; ACTL6B; CHD4; CUX1; HBP1; RCOR1; LMCD1; CREG1; TAF1D; ZKSCAN1; MAFF; BRD2; PTRF; HHEX; IRF7; ST18; RNF10; RLF; MYCN; MNAT1; SND1; NFATC1; STAT1; BHLHE40; ATF3; CHD1; MED13; MTF2; ZSCAN18; KLF11; CSDE1; ERG; GATA6; PHF20; NR4A2; SHOX2; SCAND1; SMAD2; KDM5D; HEY2; NFE2; ZNF536; ZNF165; NFAT5; YBX1; CAMTA1; ZNF652; TOX3; IRF6; DMTF1; TRIM16; NR1D2; PAX6; GRHL2; SREBF1; INSR; SOX17; OSR2; POU4F1; BAZ2B; TOB1; MAF; NEUROD1; SMARCA1; PLAGL1; JUNB; BTG1; TBX3; MEIS1; SOX9; TXNIP; HMG20B; PEG3
Down-regulation	70	CCNA2; HMGA2; ATF1; TSC22D3; FOXM1; MYBL2; PCBD1; CDK2; BRCA1; XBP1; NUP62; CAPN15; WHSC1; HNRNPD; DEK; E2F8; CBX5; RBM14; ACTL6A; IFI16; HOXC4; TRIB3; HOXA1; PLAGL2; CBFB; ZFP36L1; RBL1; CENPF; TFDP1; PA2G4; CALR; BATF; SP140L; SP3; HOXB6; HOXB2; TGFB1; HMGB1; CBX3; HOXB7; STAT6; CBX6; MED7; SLC2A4RG; RXRA; SUV39H1; BAZ1B; YEATS4; RBBP8; EYA2; HMGB2; MAFB; FOXD1; PTTG1; VDR; HMGB3; TP63; PRKDC; SALL1; MYBL1; SATB2; SAP30; HOXC6; POU2AF1; MECOM; SUB1; SMAD1; PPARG; CREB1; NFATC3