Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID13142 Cgp-60474 GSE70138 HME1 Human 24h 0.37uM EID0080
Types Number Response transcription factors
Up-regulation 326 PBX2; KAT2B; EHMT2; CALCOCO1; HOXA3; ZFPM2; SALL2; MEIS2; ZNF671; IKZF1; EZH1; PARP1; SHOX; GLI1; CSDC2; SOX2; THRA; ZSCAN9; THRB; ZNF76; IRF9; PROP1; NFATC4; GBX1; LEF1; FOXH1; CNBP; L3MBTL1; PCBD1; HSF4; TFEC; ZBTB7B; MEF2C; CALR; LHX3; APBB1; IKZF4; ZFHX2; PEX2; MYT1; ING4; BAZ2A; TWIST1; ZNF117; E2F5; CBX7; VENTX; RING1; RBFOX2; E2F4; DLX6; SMARCC2; ZNF688; TCF15; ZFHX3; ZNF506; ZNF154; PRDM14; HOXB5; ZNF667; ZSCAN18; SOX5; HDAC5; ZKSCAN4; ZIC3; GLI2; SSX7; AFF2; TCEA2; HNF1B; HAND2; HOXB1; RFX1; CERS6; CIITA; ZSCAN31; EGR1; ZXDC; CIC; NRL; ALX3; ZNF345; TBX19; TFEB; DCC; ZKSCAN3; RAX; DLX5; ZNF224; SOX17; MZF1; HIVEP3; SSBP3; TERF1; ATN1; EMX1; ZBTB44; ZNF358; MED12; ZNF362; ACTL6B; ASCL3; CARF; ARNT; ZNF589; ZNF264; KMT2D; DAXX; ZNF467; TEAD3; NEUROG1; RORC; ZNF768; EP300; LDB1; HMX1; HESX1; IRF1; PAX1; SUPT3H; TSHZ2; FOS; RXRB; SPDEF; NR5A2; DLX4; ZNF682; ETV7; TULP1; PSMC3; NFKBIB; ZNF507; ZNF606; PGR; ZBTB20; CBX2; KDM4C; TLX1; ZIM2; MED15; TBX10; CREB3L2; SIX5; KLF13; ZNF493; ZNF444; ZNF652; EVX1; NFE2L3; ZBTB48; RFX2; SRCAP; PHOX2B; HOXC5; ZNF500; STAT2; ZNF423; RUVBL1; ATOH1; NR5A1; ZNF135; ZNF711; ZNF771; IRF5; PRDM12; MYCBP; LIN28A; HOXD3; FOXA2; ZSCAN16; FOXJ1; SUPT6H; BNC2; PAX6; TFDP2; ZNF33B; THRAP3; TFDP1; CAMTA1; HLF; TOX3; HAND1; EP400; ZNF665; ZNF710; GFI1B; ENY2; HOXB2; SMARCB1; CREG1; ZNF415; SSX1; NEUROD1; ID4; CSDE1; CAMTA2; RFX5; NOC2L; MECP2; SUPT4H1; FOSB; TAF1; NR1I3; SOX21; ZNF248; ZNF532; PRRX1; TCF21; NR1D2; HMGA1; SRY; CREBL2; BARX1; GATA1; OVOL1; MYCL; ESR1; ZNF184; AES; ZNF350; VGLL1; KDM5C; ARRB1; SOX3; ZNF835; HHEX; SPI1; ZNF43; MEIS1; HLX; PRDM1; PHF1; CHD4; ZFHX4; SOX13; SUB1; ZNF232; SMARCA2; HOXA10; ZNF611; SP140; TCF4; ZHX2; MXD3; HLTF; SOX18; ZNF536; BBX; ZEB1; SCMH1; ERBB4; AEBP1; CTNNB1; MXI1; SOX11; HEY2; NFATC1; MITF; BACH2; ZBED2; ZNF205; INSM1; DBP; ATF3; PBRM1; IRF8; ZNF544; ARNT2; PBX3; ID3; CBX4; ZNF304; WT1; GRHL2; PEG3; ZNF394; RNF10; MTA1; HOXB7; AR; ID1; ZNF331; HMGN3; NFIC; LMCD1; ZNF551; NR4A1; SLC2A4RG; ASCL1; TXNIP; MYCN; KLF1; MEOX2; ZNF93; CREB5; ZNF195; TGFB1I1; POU2AF1; MYRF; HOXB6; BCL11A; HDAC9; SALL1; PLAGL1; FOXF1; TGFB1; TBX2; CREB1; HEY1; PITX1; NR4A2; VPS72; ZIC1; SMARCA1; IRF6; JUP; TRIM22; CRYM; MSX1; ZNF91; PSIP1; NR2F1; ID2; MECOM; MYBL1; NKX2-1
Down-regulation 225 MYC; FHL2; CDK7; TSC22D3; XBP1; NUP62; NFKBIA; FOSL1; TBPL1; NFIL3; MTF2; ADRB2; SOX4; CCNA2; ADNP; HES1; KAT6A; CRK; DNAJC2; TBL1X; FOXO3; TAF5; CRY1; MNT; SETD2; TBP; E2F6; ARNTL; ZNF266; CEBPB; HOXA5; RNF138; SNW1; ZNF263; RNF4; CBX3; TAF9; BRIP1; CNOT1; MEF2A; PHF20; ZBTB11; EZH2; FOXN2; ZNF146; ZZZ3; NCOA6; PPRC1; HIF1A; ZNF473; SNAI2; CTCF; MED6; RCOR1; TAF1D; RBM14; ZNF189; CTBP2; HOXA1; APEX1; REST; HSF2; NRBF2; MED27; MED23; RREB1; SNIP1; ECD; TRIM28; TRIM32; NAB1; SIX1; MED17; KDM2A; BRPF1; CENPF; NPM1; SFPQ; RBPJ; NR2F2; PRDM4; NCOA3; RAN; IRX4; YBX3; JARID2; CARM1; RBL2; WDHD1; HOXC6; BRD3; ZFP36L2; MED7; NKX3-1; ZNF302; PSPC1; RNF111; ATF7IP; TSC22D2; GMEB2; CTR9; ZBTB24; PATZ1; NELFB; ZHX3; HMGB2; TRIP6; GABPA; ZMYM2; ANKRD1; USP22; TP63; TEAD4; PIAS1; DPF2; JUND; BTAF1; SUZ12; DR1; SOX15; SMARCA5; EED; CDK8; PLAGL2; AGO2; ZNF337; BCL10; SERTAD2; TCERG1; ZFP64; TCF12; ZBTB7A; EGR4; ETS1; HOXC10; HIVEP2; CHD1; UBE2B; FOXG1; NKRF; TRIM29; SIAH2; SMAD5; MED4; MED1; NCOA4; ZNF12; TLE1; CEBPG; NPAT; TFAP2C; BLM; KLF6; ZNF432; DDX5; CCDC59; HNRNPD; ZFP36L1; PURA; MYB; TRIP4; CEBPZ; LPIN2; SIX2; SP3; KLF4; BIRC2; NFYB; FOXK2; RLF; ING2; BHLHE40; ELK3; HOXA11; TBX3; GATAD2A; ZBED4; BCL11B; STAT3; VEZF1; FOSL2; TRIB3; NRIP1; NFKB1; PMS1; ABL1; IFI16; MLXIP; ZNF443; RYBP; EDF1; POU4F1; ERBB2; FOXD1; ZNF131; SPEN; FOXO1; ZNF226; PIR; TAF10; DEK; PUF60; KLF5; RBPMS; UBE2I; SATB2; SUV39H1; MAFB; TOB1; PCGF2; AFF1; KDM5D; TLE4; NR3C1; YWHAB; NFIB; BASP1; SAP30; DLX2; SOX9; ELF5; TSC22D1; GATA6; SATB1; NFATC3