Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID13116 Gsk-461364 GSE70138 HME1 Human 24h 3.33uM EID0080
Types Number Response transcription factors
Up-regulation 53 MTF2; PIAS2; TAF4; HSF1; YAF2; KDM2A; MBD2; RREB1; CHD3; KDM5B; PIAS1; ING3; NR2F2; KMT2A; HSF2; RNF111; TRIM24; ZNF430; IRX5; COPS5; ING2; KMT5A; MED1; LPIN2; PSPC1; ZMYND8; ZNF148; EDF1; RNF10; BANP; DLX5; EYA1; MECOM; ERG; MXI1; AFF1; PEG3; MTA1; TGFB1; SSX1; MSX1; ZNF281; TOX3; ZBTB16; SAP30; KLF9; TRPS1; HOXC10; GATA6; ESR1; WT1; BHLHE41; NFATC3
Down-regulation 43 ACTL6A; XBP1; FOSB; ZFHX4; NR1I2; SOX11; RING1; LMCD1; NR2F6; HMGA2; ID4; FOXN3; ID1; NFE2L3; HEY1; BASP1; CARHSP1; SUB1; RBBP8; HMGB1; TGFB1I1; POU2AF1; TCF4; CTNNB1; ZBED2; NR4A1; ATF3; SP3; MEOX2; JUND; ZSCAN18; ZEB1; EGR2; LOXL2; KLF2; TRIM29; KLF6; ID3; AEBP1; ETS2; ELF5; CREB1; EGR1