Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID13093 Pd-0325901 GSE70138 HME1 Human 24h 0.37uM EID0079
Types Number Response transcription factors
Up-regulation 174 TLE1; PBX1; NFIL3; RFX5; TCEB2; NFKBIA; CEBPD; TRIM16; ELF3; FOXO3; OSR2; MEIS1; SMARCD2; ZNF140; IRF9; CALCOCO1; FOXO4; RXRB; ATF3; IRF1; PNRC1; ARNT; PBXIP1; HES1; SMAD4; ZFHX3; DLX4; TEAD3; NFE2L2; MTA1; LMCD1; SALL2; RING1; EHMT2; ZNF14; TOX; ETV7; TCEA2; NFE2L1; WNT4; MAF; ZMIZ1; RNF10; PRDM2; ZSCAN31; EZH1; ZKSCAN4; HIPK1; PIR; CSDC2; SSBP2; CHD3; CBX7; PPARGC1A; TAF11; SREBF1; MXI1; TFDP2; KDM4A; PEG3; BAZ2B; BRD2; MEIS2; TXNIP; TRIM22; ZNF512B; ARID5B; RXRA; ZNF467; ZNF219; EP300; HDAC5; ASCL1; IRF6; NFKB2; TLE4; ZNF768; ZNF304; MAFB; SP3; SP110; ZNF516; BCL6; IRF5; ZNF264; DACH1; MEOX2; INSM1; STAT6; KLF4; GRHL2; AES; ZNF423; CDIP1; ADRB2; PROX1; HMGN3; STAT5A; HDAC9; CREG1; SUPT7L; NCOR2; ELF1; ZNF266; TP53; HDAC4; KAT6B; ZNF350; HOXA5; KLF11; PITX1; DBP; ZHX2; SALL1; MYCN; ERBB2; KLF10; FLI1; TGFB1I1; LITAF; HTATIP2; JUND; TOB1; ID3; NCOA2; PLAG1; HBP1; NKX2-1; ELF4; GATA6; RCOR3; KLF5; FOXO1; DAXX; PFDN5; JUP; ZNF224; SHOX2; FOXL2; SP140L; BTG1; ZNF532; JAK2; TRIP6; FOSL2; ESR1; CREBL2; TSC22D3; ETS2; ZNF652; HHEX; ID4; EHF; BCL3; HEY2; FOXN3; ZSCAN18; AHR; PLAGL1; ZBTB16; ERG; PAX6; SOX11; SMAD6; ZNF91; PDLIM1; SOX17; VGLL4; MECOM; TCF4; ID1; ZFPM2; RELB; CREB1
Down-regulation 87 HMGA2; CCNA2; SUV39H1; FOSL1; BRCA1; DNMT1; MYC; ETV1; FOXM1; RAN; SUZ12; TRIB3; NUP62; CHAF1B; RUVBL1; BHLHE40; EZH2; ETV4; TFDP1; MYBL2; WDHD1; TCERG1; HMGB2; NPAT; CENPF; BAZ1A; PA2G4; MYCBP; PSMC3IP; TFAM; AGO2; ELK3; ENO1; BMI1; XRCC6; ASH2L; E2F1; NOC2L; RBM14; RBL1; HMGA1; PPRC1; BCLAF1; SIM2; EGR1; ILF2; HNRNPD; XBP1; CCNE1; CCNC; ZMYND11; DNAJC2; YEATS4; MYBL1; NPM1; ARNTL2; USP16; GTF3A; DEK; TGFB1; HMGB1; SMAD3; EGR3; C1QBP; CDK2; RUVBL2; CBFB; CBX3; FOS; KLF6; YWHAB; NKX3-1; HLTF; HMGB3; FOXD1; RUNX3; ETV5; PPARG; SOX9; PAX5; THAP11; SATB2; POU4F1; LEF1; KDM5D; HOXC6; NFATC3