Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID13027 I-bet-762 GSE70138 HME1 Human 24h 1.11uM EID0079
Types Number Response transcription factors
Up-regulation 71 MEF2C; KAT6A; PPARG; FOXJ1; PHOX2A; SMAD3; POU3F2; MNAT1; DLX5; CHD3; MEF2D; HSF1; PPARGC1A; ZNF268; DLX4; TGFB1; KDM2A; SREBF1; HIPK2; NKX2-1; SNAI1; RCOR1; ZBTB16; RERE; BHLHE41; CUX1; MECOM; MYCN; SPEN; PROX1; NEUROD1; IRF8; NFIB; HOXD3; KLF10; EGR3; HDAC5; KLF11; FOXG1; WWC1; SOX17; HIC2; IRF7; SMAD7; CREB3L2; KAT6B; NR4A2; TCF4; NR4A1; MLXIP; FOSB; NR3C2; EGR1; TXNIP; HMBOX1; NR5A2; NFAT5; TFEC; CREG1; ERG; ZFPM2; GATA6; HOXD1; SATB2; ASCL1; FLNA; ESR1; HDAC9; ST18; ZBTB18; NFATC3
Down-regulation 56 CCNA2; TGIF1; BRCA1; FOXM1; SUV39H1; LITAF; STAT6; ATF1; ZNF432; XRCC6; EYA2; LIN28A; HOXB2; TFAP2C; CBX6; TRIM29; ZNF148; MED17; SUB1; ZHX2; DEK; SIX2; FOXD1; SOX11; SMAD1; CCNC; PTTG1; ZFP36L1; EHF; HMGB3; PBX3; HTATIP2; AES; BBX; ISL1; TRIM16; CREBL2; NANOG; SIAH2; TP63; RBPMS; TOX; IFI16; MAFB; THAP11; MNDA; ZNF43; TRIM22; TBL1X; BTG1; MEIS2; BASP1; TOB1; TBX3; CREB1; ZNF586