Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12872 Osimertinib GSE70138 HME1 Human 24h 0.04uM EID0039
Types Number Response transcription factors
Up-regulation 20 IKZF1; MEF2C; FLI1; IRF5; ELK3; SSBP2; IFI16; IRF4; DDIT3; CITED1; ETV5; TWIST1; RORA; MEIS2; ERG; ZFP36L1; TCF4; CREB1; HOXC6; AEBP1
Down-regulation 24 THAP7; FOXA2; CEBPB; LITAF; TFDP2; CD3D; JUNB; HIC2; GRHL2; ZBTB18; FOXF1; NR4A2; DLX5; EHF; ST18; IRF6; ID1; MNDA; DLX2; ISL1; MAFB; MYB; TOX3; NFE2L3