Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12843 Gsk-1059615 GSE70138 HME1 Human 24h 0.04uM EID0039
Types Number Response transcription factors
Up-regulation 62 FOXO4; GTF2F1; HDAC5; TCEA2; SALL2; TCEA1; AES; HES1; SMAD4; SOX4; SUPT3H; HBP1; MTA1; TAF12; NR1H2; SP110; BTF3; PFDN5; CREG1; KDM5B; APEX1; BACH2; CENPB; SCAND1; COPS5; SND1; CSDE1; TADA3; AHR; MAFF; CALCOCO1; FOSB; YBX1; TRIP6; CREBL2; ZNF593; VGLL4; BAZ2B; ELK3; TERF1; NRIP1; LITAF; PBX1; PDLIM1; JARID2; HMGA1; NCOA2; ID4; TAF10; TGFB1; IRF7; ELF3; ID1; INSR; TWIST1; HDAC9; TGFB1I1; SOX11; MEIS1; ID3; HOXB2; BASP1
Down-regulation 35 CCNA2; ZNF274; BHLHE40; MYBL2; CDK2; EZH2; CENPF; ARL2BP; HMGB2; WDR77; ING2; STAT1; RNF6; FOXM1; ARNT2; LEF1; TRIB3; CCNH; BLM; NR2F1; YWHAB; SAP30; ZMYM2; PIR; ZNF443; ZBTB18; MAGED1; PBX3; ZSCAN18; TXNIP; ASCL1; SUV39H1; TBX3; MYB; TOX3