Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12840 Gsk-1059615 GSE70138 HME1 Human 24h 1.11uM EID0039
Types Number Response transcription factors
Up-regulation 141 FOXO4; HDAC6; PNRC1; HBP1; BRD8; TSC22D3; EZH1; GTF2F1; ZNF266; ZBTB48; NONO; TCEA2; GON4L; TERF2; ZNF688; TBL1X; HDAC5; RXRB; TAF12; UIMC1; NCOA3; HINFP; SIRT7; ZBTB43; PHF1; TCF25; RNF10; TTF1; DDIT3; HDAC4; SETDB1; ING4; EHMT2; MTA1; USP21; MXI1; PRDM2; PCGF1; GTF2IRD1; ZNF23; NFIL3; SALL2; AIP; DBP; ZNF500; ZNF384; THRA; NPAS2; SND1; CBX7; ATF4; NR1H2; PBX1; ZSCAN32; BRD2; ING3; ZNF175; GFI1; SUPT4H1; KLF9; TLE1; TCEA1; BAZ1B; ZHX2; RERE; BCL6; ZZZ3; SIX1; FLI1; BTF3; CALCOCO1; PFDN5; SP110; ZMIZ2; INSR; ZNF24; SOX13; IFI16; EMX2; NR1H3; BCL11A; ZMIZ1; SSBP3; PBXIP1; KMT2A; HEY2; AHR; CREBL2; ARNTL; KLF7; ZNF83; ZNF232; CXXC1; SOX4; BHLHE41; EYA2; ZNF580; ZBTB38; FOXO1; BAZ2B; ZNF467; L3MBTL1; KDM2A; SAP18; HDGF; ESR1; NR1D2; TRPS1; ELF5; NR4A2; SP100; CSDE1; POU2AF1; PPP1R13L; IRF9; ZNF512B; ZNF331; PDLIM1; ID4; APEX1; BRD4; HTATIP2; FOSB; ZBTB20; HMGN3; ELF3; MAFB; SOX17; ZSCAN16; ERBB4; ZNF117; BTG1; TXNIP; TRIP6; KLF11; MNDA; ZBTB16; HMG20B; TAF10; RELB; SOX11
Down-regulation 48 MYCBP; GTF2A2; TRIB3; BHLHE40; RUVBL1; DNMT1; ZNF274; WDR77; TCF21; UBE2L3; YWHAB; MED21; HIRA; ACTL6A; TSC22D2; FOXF1; MECOM; ADRB2; RB1; PTRF; TOX3; SFPQ; HOXB6; NR2F1; SNAI2; RAN; ETS2; ZNF652; LEF1; JUP; HMGB2; ENO1; FLNA; PBX3; MYBL1; JUNB; CALR; ZSCAN18; KLF10; FOSL1; HIC2; KLF6; ETS1; ATF3; NFE2L3; AEBP1; CREB1; ZNF586