Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID12839 Gsk-1059615 GSE70138 HME1 Human 24h 3.33uM EID0039
Types Number Response transcription factors
Up-regulation 147 IKZF1; FOXO4; BRD8; TSC22D3; HBP1; NCOA3; KLF13; PNRC1; CBFA2T2; HDAC6; NFIL3; EZH1; HDAC5; ING4; TERF2; TOB1; DDIT3; INSR; BRD2; USP21; SIRT2; ZNF212; GON4L; EYA2; SETDB1; SIRT7; ZBTB43; TRIP4; ZHX2; HINFP; ZMIZ1; SUPT5H; MAFG; PAXBP1; UIMC1; ZNF266; ASXL1; CXXC1; VGLL4; RXRB; NCOR1; RNF10; MZF1; TCEA2; NPAS2; KAT2A; TOX; TLE1; BRD4; GTF2IRD1; ARNTL; NONO; BACH2; COPS2; ZNF3; ZNF692; MED23; BTG1; RBM39; ATF4; PRDM2; MTA1; NFATC1; BCL11A; ATN1; TRIM16; NR1H3; SETD2; CALCOCO1; BAZ1B; SND1; HOXD1; ZNF24; ZNF423; CDC5L; SPDEF; ZNF160; CEBPG; BAZ2B; TAF5; LMCD1; PBXIP1; SCAND1; PLAG1; PPP1R13L; BHLHE41; KLF7; SSBP3; ZNF131; ZNF354A; L3MBTL1; KLF11; SOX4; CERS6; JUND; TCEA1; FOSB; SP2; SIN3B; PSPC1; KLF9; BCOR; LYL1; TRAK1; SP100; ZNF195; ESR1; TCF7; ELF3; SSBP2; PDLIM1; HOXC6; BANP; RYBP; MED24; PHF20; RUNX3; SREBF1; ARID4B; CEBPD; TRPS1; ZNF721; CBFA2T3; IRX5; RSF1; IRF8; ZSCAN31; INSM1; MYRF; NKX3-1; BCL3; PHIP; PBX1; ZNF165; KDM5D; MXI1; ZNF264; NCOA2; HDAC9; IRF7; ELF5; HMG20B; MEIS1; RELB; HOXC10; ZNF91; WT1
Down-regulation 82 MYCBP; GTF2A2; RUVBL1; BHLHE40; WDR77; TEAD1; HMGA2; DNMT1; CLOCK; SMAD3; TCF21; TRIM32; NR2F1; DR1; ZNF274; CCNA2; NEDD8; RBBP4; FOXF1; SFPQ; CDK2; HMGB2; DRAP1; MED7; YAP1; HNRNPD; MNAT1; SUB1; PARP1; REST; GATAD2A; ING2; ZNF528; FLNA; PSIP1; EGR4; LZTS1; ANKRD1; WWC1; PITX2; EGR3; MYBL1; ELK3; ZBTB18; BLZF1; RXRA; FOSL1; NCOA4; SOX15; SAP30; PBX3; CD3D; ETS2; RUVBL2; EGR1; ID1; MYCL; CBFB; CCNH; HOXB6; NR4A1; TSC22D1; ASCL1; ZBED2; ENO1; BCL11B; ID3; CITED2; ASH2L; ZFPM2; NR2F2; TFEC; HIC2; ETS1; ZSCAN18; ZEB1; NFE2L3; TFDP1; ZNF544; OSR2; ID2; ZNF586