Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID12816	Ibrutinib	GSE70138	HME1	Human	24h	1.11uM	EID0039

Response Information :

Types	Number	Response transcription factors
Up-regulation	87	SALL2; TRIM16; TCEA2; TFDP2; IRF1; FOXO3; NFE2L2; NFIL3; CREG1; TSC22D3; RBFOX2; ING4; TGIF2; PNRC1; LITAF; EHMT2; CEBPD; TCEB2; TP53; PBXIP1; TFAP2A; IRF6; VGLL4; PBX1; PCBD1; SCAND1; TOX; IFI16; TCF7L1; HOXA5; NR1H3; STAT4; ZSCAN31; NFKBIA; TRIM29; ARID5B; BTF3; MECOM; MKL2; SMARCD2; CREB3; SREBF1; ZHX2; SMAD6; ID1; HBP1; ZNF580; ZFP36L2; ERBB2; ID3; ZMIZ1; JUP; ATF3; MTA1; ARNT2; MXI1; PHF20; MEIS2; NKX2-1; AHR; JUND; ELF3; CUX2; CD3D; MAF; ZNF423; MEOX2; HMGN3; SP140L; BCL3; SALL1; EN1; MAFB; KLF5; TDP2; CBX7; TAL1; EMX2; GATA6; NCOA2; PDLIM1; OSR2; ESR1; TRIP6; WT1; ZNF532; DAXX
Down-regulation	45	ETV1; HMGA2; BHLHE40; CCNA2; TLE1; IL16; XBP1; FOS; IRF4; ZBTB18; FOSL1; BCLAF1; CREB3L1; PAX5; EGR3; BMI1; EGR1; ING3; BAZ1A; BRCA1; SIM2; PURA; HMGA1; MYB; CBFB; MNAT1; ARNTL2; SPIB; CHD1; CCNE1; DLX5; SATB2; ELF5; TRPS1; KLF6; BASP1; PPARG; NKX3-1; KLF2; FOXD1; TCF4; SUV39H1; CREB1; AEBP1; PLAGL1