Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID12763	Tivozanib	GSE70138	HME1	Human	24h	0.37uM	EID0039

Response Information :

Types	Number	Response transcription factors
Up-regulation	81	SMAD3; BBX; NR1H2; OVOL2; STAT2; HIPK2; CTNNB1; CBX4; TXNIP; KLF3; ELK3; GATA3; MED15; ZKSCAN1; CIC; FOXA1; ZNF264; SHOX2; BAZ2A; SALL2; DAXX; MDM4; HBP1; ZNF224; SMAD1; ST18; PRDM1; BTG1; IRF1; PBXIP1; NR1D2; RARG; PRRX1; NR5A2; PAX6; STAT4; MNAT1; MAFF; ZNF665; BAZ1A; HDAC9; ILF2; BACH1; NR4A2; HIVEP2; ZNF506; INSM1; NEUROD1; STAT5A; KDM5D; BACH2; VGLL1; EMX2; IRF6; ZNF124; CAMTA1; NFAT5; CNOT3; MTA1; ZFP36L2; JUP; ZSCAN31; ERBB4; ZNF304; ZNF423; ZFPM2; ZNF551; ZNF430; ZNF217; HIC2; TWIST1; APEX1; ATF3; ARNT2; PEG3; MED1; ZBTB18; BHLHE41; MAFB; HOXB2; TOX3
Down-regulation	39	PDLIM1; PURA; SMAD7; SMAD6; PIAS1; MED21; TBL1X; ING2; NR1H3; STAT6; TLE4; NCOA1; RUNX3; PPARGC1A; NR2F2; CTR9; SMAD2; SOX10; CBFB; MBD2; DNAJC2; IKBKAP; EGR2; GATA6; IFI16; FOXO1; ZBTB16; EYA1; TOX; SIX2; TGFB1I1; MYBL1; TLE2; ELF5; PIR; ZNF532; ID1; HOXC10; ZNF586